Key risk factors of asthma-like symptoms are mediated through infection burden in early childhood

JN Kyvsgaard, N Brustad, LM Hesselberg… - Journal of Allergy and …, 2024 - Elsevier
Background Risk factors of asthma-like symptoms in childhood may act through an
increased infection burden because infections often trigger these symptoms. Objective We …

Genetic susceptibility to acute viral bronchiolitis

A Pasanen, MK Karjalainen, M Korppi… - The Journal of …, 2024 - academic.oup.com
Background Acute viral bronchiolitis is a major cause of infant hospitalizations worldwide.
Childhood bronchiolitis is considered a risk factor for asthma, suggesting shared genetic …

Mechanistic modelling of allergen-induced airways disease in early life

HJ Pybus, P Dangarh, MYM Ng, CM Lloyd… - Scientific Reports, 2025 - nature.com
Asthma affects approximately 300 million individuals worldwide and the onset
predominantly arises in childhood. Children are exposed to multiple environmental irritants …

Burden and subtypes of early life infections increase the risk of asthma

JN Kyvsgaard, LM Hesselberg, RB Sunde… - The Journal of Allergy …, 2024 - Elsevier
Background Early life respiratory tract infections have been linked to the development of
asthma, but studies on the burden and subtypes of common infections in asthma …

Changes in environmental exposures over decades may influence the genetic architecture of severe spermatogenic failure

M Cerván-Martín, S González-Muñoz… - Human …, 2024 - academic.oup.com
STUDY QUESTION Do the genetic determinants of idiopathic severe spermatogenic failure
(SPGF) differ between generations? SUMMARY ANSWER Our data support that the genetic …

ST2 and IL‐33 polymorphisms and the development of childhood asthma: a prospective birth cohort study in Finnish children

JT Teräsjärvi, L Toivonen, J Mertsola, V Peltola, Q He - APMIS, 2024 - Wiley Online Library
The ST2/IL‐33 signaling pathway has an important role in the host inflammatory response.
Here we aimed to study the association of ST2 and IL‐33 polymorphisms with serum soluble …

[HTML][HTML] Association between asthma and IgG levels specific for rhinovirus and respiratory syncytial virus antigens in children and adults

M Mauclin, A Guillien, K Niespodziana… - Journal of Allergy and …, 2025 - Elsevier
Background Viral infections in childhood, especially to rhinovirus (RV) and respiratory
syncytial virus (RSV), are associated with asthma inception and exacerbation. However, little …

[图书][B] From preschool wheeze to childhood asthma: the role of genetics and environmental factors

AE Filiou - 2024 - search.proquest.com
Background: Respiratory illness with wheeze is very common at preschool age and is often
the first clinical manifestation of asthma. Two-thirds of preschool wheezers outgrow their …

ФАКТОРЫ РИСКА РАЗВИТИЯ И ОБОСТРЕНИЯ БРОНХИАЛЬНОЙ АСТМЫ: СОВРЕМЕННЫЙ ВЗГЛЯД НА ПРОБЛЕМУ

ДА АНДРЕЕВ, НН КАМЫНИНА - elibrary.ru
Введение. Причины развития бронхиальной астмы (БА) сложны и не до конца
изучены. Понимание причинных факторов развития БА является важным шагом на …