Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

The use of stem cells has been reported to improve hair regrowth in several therapeutic
strategies, including reversing the pathological mechanisms, that contribute to hair loss …

Perturbations in the transcriptional programs specifying epidermal differentiation cause
diverse skin pathologies ranging from impaired barrier function to inflammatory skin disease …

The tarsal glands of Meibom (glandulae tarsales) are large sebaceous glands located in the
eyelids and, unlike those of the skin, are unassociated with hairs. According to Duke-Elder …

In mammalian skin, multiple types of resident cells are required to create a functional tissue
and support tissue homeostasis and regeneration. The cells that compose the epithelial …

Alterations in nonshivering thermogenesis are presently discussed as being both potentially
causative of and able to counteract obesity. However, the necessity for mammals to defend …

Apolipoprotein C1 (apoC1), the smallest of all apolipoproteins, participates in lipid transport
and metabolism. In humans, APOC1 gene is in linkage disequilibrium with APOE gene on …

Atopic dermatitis (AD) is characterized by allergic skin inflammation. A hallmark of AD is dry
itchy skin due, at least in part, to defects in skin genes that are important for maintaining …

The human apoCs (ie, apoC1, apoC2, and apoC3) are often portrayed as members of 1
consistent protein family because of their similar distributions among lipoprotein classes …

Mast cells play as the major effector cells in immediate hypersensitivity through activation via
the high-affinity IgE receptor, FcɛRI, although many other functions have recently been …