Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

Highlights•The unique mycobacterial cell wall is a layered structure of carbohydrates and
lipids.•The architecture and biosynthesis of the cell wall have largely been …

Real-time localization and microbial activity information of indigenous gut microbiota over an
extended period of time remains a challenge with existing visualizing methods. Here, we …

Most bacteria are surrounded by a cell wall that contains peptidoglycan (PG), a large
polymer composed of glycan strands held together by short peptide cross-links. There are …

Introduction Mycobacteria assemble a complex cell wall with cross-linked peptidoglycan
(PG) which plays an essential role in maintenance of cell wall integrity and tolerance to …

Enterococcus faecalis and Enterococcus faecium are Gram-positive commensal gut bacteria
that can also cause fatal infections. To study clinically relevant multi-drug resistant E …

The lack of effective therapeutics against emerging multi-drug resistant strains of
Mycobacterium tuberculosis (Mtb) prompts the identification of novel anti-tuberculosis …

Cell wall peptidoglycan is a heteropolymeric mesh that protects the bacterium from internal
turgor and external insults. In many rod-shaped bacteria, peptidoglycan synthesis for normal …

Cell walls are barriers found in almost all known bacterial cells. These structures establish a
controlled interface between the external environment and vital cellular components. A …

The general lack of permeability of small molecules observed for Mycobacterium
tuberculosis (Mtb) is most ascribed to its unique cell envelope. More specifically, the outer …