Aim: Despite numerous published prognostic methylation markers for renal cell carcinoma
(RCC), none of these have yet changed patient management. Our aim is to systematically …

Context The 5-yr survival of early-stage renal cell carcinoma (RCC) is approximately 93%,
but once metastasised, the 5-yr survival plummets to 12%, indicating that early RCC …

Background To explore the possible mechanism by which curcumin reverses the sunitinib
resistance in clear cell renal cell carcinoma (ccRCC). Methods A sunitinib-resistant ccRCC …

Objective To explore the effect of curcumin on the proliferation of renal cell carcinoma and
analyze its regulation mechanism. Methods In RCC cell lines of A498 and 786-O, the effects …

This investigation aims to study the reversal effect of the Chinese herbal compound
SanHuang decoction on axitinib resistance in clear cell renal cell carcinoma (ccRCC) cells …

Background ADAMs (a disintegrin and metalloproteinase) have long been associated with
tumor progression. Recent findings indicate that members of the closely related ADAMTS …

The “A Disintegrin and Metalloproteinase with Thrombospondin Motif”(ADAMTS) family of
genes is involved in the occurrence and development of different cancers. However, the …

ADAMTS 18 dysregulation plays an important role in many disease processes including
cancer. We previously found ADAMTS 18 as frequently methylated tumor suppressor gene …

Objective To investigate the effect of curcumin on viability of clear cell renal cell carcinoma
(ccRCC) and analyze its possible mechanism. Methods In cell lines of A498 and 786-O, the …

Abstract Chromosome region 3p12‐14 is an important tumour suppressor gene (TSG) locus
for multiple cancers. ADAMTS 9, a member of the metalloprotease large family, has been …