The chemistry of phenols tends to be ignored in organic chemical textbooks and to be lost
amongst the many classes of functional derivatives. This volume is not intended to provide a …

Glioblastoma (GBM) contains a self-renewing, tumorigenic cancer stem cell (CSC)
population which contributes to tumor propagation and therapeutic resistance. While the …

The aryl O-carbamate (ArOAm) group is among the strongest of the directed metalation
groups (DMGs) in directed ortho metalation (D o M) chemistry, especially in the form Ar …

A highly efficient process of aerobic oxidative coupling of 2-naphthol derivatives catalyzed
by 1 mol% of Cu (OH) Cl⊙ TMEDA has been developed. Enantioselective oxidative …

Splitomicin (1) and 41 analogues were prepared and evaluated in cell-based Sir2 inhibition
and toxicity assays and an in vitro Sir2 inhibition assay. Lactone ring or naphthalene …

We studied four cyclometallated Pt (II) complexes, in which the thiazo-coumarin ligands (Pt-
2, Pt-3 and Pt-4) or the phenylthiazo ligand (Pt-1) were directly cycloplatinated. Pt-2 shows …

We report 3-(4, 5-diphenyl-1H-imidazol-2-yl) naphthalen-2-ol (DPIN) as an interesting
luminescent material displaying ESIPT with a large Stokes shift of∼ 180 nm even in …

A new straightforward synthesis of dinaphtho [2, 3-b: 2′, 3′-f] thieno [3, 2-b] thiophene
(DNTT) derivatives from readily available 2-methoxynaphthalenes is described. Thus, newly …

Directed lithiation of substituted aromatics and heterocycles containing a directing
metalating group with alkyllithium in anhydrous tetrahydrofuran or diethyl ether at low …

Attempted perilithiation of 1-naphthamides with their 2-positions blocked leads only to
nucleophilic attack on the aromatic ring, but perilithiation of naphthalenes bearing 1 …