The role of p53 signaling in colorectal cancer
MC Liebl, TG Hofmann - Cancers, 2021 - mdpi.com
Simple Summary The transcription factor p53 is a crucial tumor suppressor that regulates
diverse cellular responses to protect against cancer development. Deactivating p53 …
diverse cellular responses to protect against cancer development. Deactivating p53 …
Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response
M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …
microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer
JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …
could be observed in women who infected with papillomavirus, regular oral contraceptives …
Colorectal cancer: Genetic alterations, novel biomarkers, current therapeutic strategies and clinical trials
Colorectal cancer (CRC) is the third most commonly detected cancer with a serious global
health issue. The rates for incidence and mortality for CRC are alarming, especially since …
health issue. The rates for incidence and mortality for CRC are alarming, especially since …
Interactions among lncRNAs, miRNAs and mRNA in colorectal cancer
XJ Tang, W Wang, SS Hann - Biochimie, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …
recently emerged as one of the largest and significantly diverse RNA families whereas …
The HOTAIR/miR-214/ST6GAL1 crosstalk modulates colorectal cancer procession through mediating sialylated c-Met via JAK2/STAT3 cascade
B Liu, Q Liu, S Pan, Y Huang, Y Qi, S Li, Y Xiao… - Journal of Experimental …, 2019 - Springer
Background The regulatory non-coding RNAs, including long non-coding RNAs (lncRNAs)
and microRNAs (miRNAs), emerge as pivotal markers during tumor progression. Abnormal …
and microRNAs (miRNAs), emerge as pivotal markers during tumor progression. Abnormal …
STAT3 as a newly emerging target in colorectal cancer therapy: Tumorigenesis, therapy response, and pharmacological/nanoplatform strategies
M Hashemi, S Abbaszadeh, M Rashidi, N Amini… - Environmental …, 2023 - Elsevier
Colorectal cancer (CRC) ranks as the third most aggressive tumor globally, and it can be
categorized into two forms: colitis-mediated CRC and sporadic CRC. The therapeutic …
categorized into two forms: colitis-mediated CRC and sporadic CRC. The therapeutic …
[HTML][HTML] Role of epigenetics in transformation of inflammation into colorectal cancer
ZH Yang, YQ Dang, G Ji - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
Molecular mechanisms associated with inflammation-promoted tumorigenesis have become
an important topic in cancer research. Various abnormal epigenetic changes, including DNA …
an important topic in cancer research. Various abnormal epigenetic changes, including DNA …
Interplay of miRNAs and lncRNAs in STAT3 signaling pathway in colorectal cancer progression
In recent decades, colorectal cancer (CRC) has turned into one of the most widespread
malignancies, and the incidence of this malignancy is expected to increase. Despite …
malignancies, and the incidence of this malignancy is expected to increase. Despite …
Long non‐coding RNA LINC01535 promotes cervical cancer progression via targeting the miR‐214/EZH2 feedback loop
H Song, Y Liu, X Jin, Y Liu, Y Yang, L Li… - Journal of cellular …, 2019 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have shown critical roles in multiple cancers via
competitively binding common microRNAs. miR‐214 has been proved to play tumour …
competitively binding common microRNAs. miR‐214 has been proved to play tumour …