SLIT2 promoter hypermethylation predicts disease progression in chronic myeloid leukemia

D Wu, Y Wang, T Zhang, M Chu, Z Xu, Q Yuan… - European Journal of …, 2022 - Springer
Background Aberrant DNA methylation plays a crucial role in the progression of myeloid
neoplasms. Previously, our literature reported that slit guidance ligand 2 (SLIT2) promoter …

MIR4435-2HG as a possible novel predictive biomarker of chemotherapy response and death in pediatric B-cell ALL

Y Torres-Llanos, J Zabaleta… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction: Although B-cell acute lymphoblastic leukemia (B-cell ALL) survival rates have
improved in recent years, Hispanic children continue to have poorer survival rates. There …

视网膜母细胞瘤结合锌指蛋白1 调控肥胖和肿瘤信号通路研究综述

谢小雷, 江佩欣, 张敬鸿, 莫骏健… - 上海交通大学学报 …, 2023 - xuebao.shsmu.edu.cn
视网膜母细胞瘤结合锌指蛋白1 (retinoblastoma-interacting zinc finger protein 1, RIZ1) 基因,
又称PRDM2 (positive regulatory domain 2) 基因, 是PRDM 基因家族一员, 其蛋白序列包含1 …

Hypermethylation of HOXA4 Gene Promoter and Its Potential Association with Disease Progression, Imatinib Resistance, High Sokal Score Risk, and Smoking …

D Radin, M Hamid, M Kargar, M Jafarinia - Russian Journal of Genetics, 2023 - Springer
The evolution of resistance to imatinib and disease progression are multifactorial events in
chronic myeloid leukemia (CML) patients. In addition to the BCR-ABL1 dependent pathway …

Global DNA Methylation analysis of imatinib resistant and sensitive K562 cells

Y Hekmatshoar - Ege Tıp Bilimleri Dergisi, 2024 - dergipark.org.tr
OBJECTIVE: Chronic myeloid leukemia (CML) is a hematological disease which is known
by the presence of Philadelphia chromosome (Ph+). BCR-ABL protein is expressed by Ph+ …

MIR4435-2HG as a Novel Predictive Biomarker of Chemotherapy Response and Death in Pediatric B-cell All

Y Torres-Llanos, J Zabaleta, N Cruz-Rodriguez… - 2023 - researchsquare.com
Background Although B-cell acute lymphoblastic leukemia (B-cell ALL) survival rates have
improved in recent years, Hispanic children continue to have poorer survival rates. There …

Epigenetic silencing of HOXA4 gene is associated with imatinib resistance, disease progression, BCR-ABL1 transcript type and smoking status among Chronic …

D Radin, M Hamid, M Kargar, M Jafarinia - 2022 - researchsquare.com
Background We aimed to investigate the role of HOXA4 gene methylation concerning
response to imatinib, and chronic myeloid leukemia (CML) progression, also investigated …

A review of RIZ1 regulation of the signal pathways in obesity and tumors

XIE Xiaolei, J Peixin, Z Jinghong… - Journal of Shanghai …, 2023 - xuebao.shsmu.edu.cn
Retinoblastoma-interacting zinc finger protein 1 (RIZ1) gene, also known as positive
regulatory domain 2 (PRDM2), is a member of the PRDM gene family whose protein …

Identificación de los cambios en los perfiles de metilación de DNA y de expresión génica, asociados a la respuesta clínica al tratamiento quimioterapéutico en …

YX Torres Llanos - repositorio.unal.edu.co
Las leucemias linfoides agudas de células B (LLA-B) son las enfermedades neoplásicas
más comunes en niños. Las tasas de supervivencia en la población pediátrica hispana son …

[引用][C] METHYLATION PATTERN OF THE RUNX3 GENE AND ITS IMPACT ON RESPONSE TO IMATINIB THERAPY IN CHRONIC MYELOID LEUKEMIA

A Mahmud, D Mohamad, M Hamid - JOURNAL OF SULAIMANI MEDICAL COLLEGE, 2023