A comprehensive summary of LL-37, the factotum human cathelicidin peptide
Cathelicidins are a group of antimicrobial peptides. Since their discovery, it has become
clear that they are an exceptional class of peptides, with some members having pleiotropic …
clear that they are an exceptional class of peptides, with some members having pleiotropic …
Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease
JM Kahlenberg, MJ Kaplan - The Journal of Immunology, 2013 - journals.aai.org
The innate immune system utilizes many approaches for defense against invading
microorganisms, including complement-mediated lysis, engulfment, formation of neutrophil …
microorganisms, including complement-mediated lysis, engulfment, formation of neutrophil …
Cathelicidins modulate TLR-activation and inflammation
MR Scheenstra, RM Van Harten… - Frontiers in …, 2020 - frontiersin.org
Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
[HTML][HTML] Pancreatic β-cells limit autoimmune diabetes via an immunoregulatory antimicrobial peptide expressed under the influence of the gut microbiota
J Sun, L Furio, R Mecheri, AM van der Does… - Immunity, 2015 - cell.com
Antimicrobial peptides (AMPs) expressed by epithelial and immune cells are largely
described for the defense against invading microorganisms. Recently, their …
described for the defense against invading microorganisms. Recently, their …
Cathelicidin impact on inflammatory cells
J Agier, M Efenberger… - Central European Journal …, 2015 - termedia.pl
Cathelicidins, like other antimicrobial peptides, exhibit direct antimicrobial activities against
a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria …
a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria …
Significance of LL‐37 on immunomodulation and disease outcome
B Yang, D Good, T Mosaiab, W Liu, G Ni… - BioMed Research …, 2020 - Wiley Online Library
LL‐37, also called cathelicidin, is an important part of the human immune system, which can
resist various pathogens. A plethora of experiments have demonstrated that it has the …
resist various pathogens. A plethora of experiments have demonstrated that it has the …
Antimicrobial peptides: clinical relevance and therapeutic implications
FP da Silva, MCC Machado - Peptides, 2012 - Elsevier
Antimicrobial peptides (AMPs) are molecules that provide protection against environmental
pathogens, acting against a large number of microorganisms, including bacteria, fungi …
pathogens, acting against a large number of microorganisms, including bacteria, fungi …
Unique features of human cathelicidin LL‐37
K Bandurska, A Berdowska, R Barczyńska‐Felusiak… - Biofactors, 2015 - Wiley Online Library
Cathelicidins are antimicrobial peptides produced by humans and animals in response to
various pathogenic microbes. This review intends to provide a brief overview of the …
various pathogenic microbes. This review intends to provide a brief overview of the …
The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice
TC Hing, S Ho, DQ Shih, R Ichikawa, M Cheng, J Chen… - Gut, 2013 - gut.bmj.com
Background Clostridium difficile mediates intestinal inflammation by releasing toxin A (TxA),
a potent enterotoxin. Cathelicidins (Camp as gene name, LL-37 peptide in humans and …
a potent enterotoxin. Cathelicidins (Camp as gene name, LL-37 peptide in humans and …
Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production
We hypothesized that the antimicrobial peptide cathelicidin has a physiological role in
regulating gut inflammatory homeostasis. We determined that cathelicidin synergizes with …
regulating gut inflammatory homeostasis. We determined that cathelicidin synergizes with …