The genomes of all organisms throughout the tree of life are compacted and organized in
chromatin by association of chromatin proteins. Eukaryotic genomes encode histones, which …

The archaeal genome is organized by either eukaryotic-like histone proteins or bacterial-like
nucleoid-associated proteins. Recent studies have revealed novel insights into chromatin …

DNA in cells is associated with proteins that constrain its structure and affect DNA-templated
processes including transcription and replication. HU and histones are the main constituents …

In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B
that assemble into octameric nucleosome particles. Archaeal histones are dimeric and …

The three domains of life employ various strategies to organize their genomes. Archaea
utilize features similar to those found in both eukaryotic and bacterial chromatin to organize …

Alba family proteins are small, basic, dimeric nucleic acid-binding proteins, which are widely
distributed in archaea and a number of eukaryotes. This family of proteins bears the distinct …

In Plasmodium falciparum, perinuclear subtelomeric chromatin conveys monoallelic
expression of virulence genes. However, proteins that directly bind to chromosome ends are …

Genomic organization impacts accessibility and movement of information processing
systems along DNA. DNA-bound proteins dynamically dictate gene expression and provide …

The archaellum is the swimming organelle of the third domain, the Archaea. In the
euryarchaeon Methanococcus maripaludis, genes involved in archaella formation, including …

TRAM is a conserved domain among RNA modification proteins that are widely distributed
in various organisms. In Archaea, TRAM occurs frequently as a standalone protein with in …