Cancer stem cells (CSCs) are subpopulation of cells which have been demonstrated in a
variety of cancer models and involved in cancer initiation, progression, and development …

Senescence is an inevitable biological process. Disturbances in glucose and lipid
metabolism are essential features of cellular senescence. Given the important roles of these …

Due to its role in maintaining the proper functioning of the cell, the pentose phosphate
pathway (PPP) is one of the most important metabolic pathways. It is responsible for …

Breast cancer (BC) is a malignant tumor that seriously endangers health in women. BC, like
other cancers, is accompanied by metabolic reprogramming. Among energy metabolism …

Nucleotide pools need to be constantly replenished in cancer cells to support cell
proliferation. The synthesis of nucleotides requires glutamine and 5-phosphoribosyl-1 …

Lung contusion and gastric aspiration (LC and GA) are major risk factors for developing
acute respiratory distress following trauma. Hypoxia from lung injury is mainly regulated by …

Targeting pentose phosphate pathway (PPP) enzymes has emerged as a promising strategy
to combat cancer. 6-Phosphogluconate dehydrogenase (6-PGD), the third critical enzyme of …

Introduction The pentose phosphate pathway (PPP) branches from glycolysis and is crucial
for cell growth, since it provides necessary compounds for anabolic reactions, nucleotide …

The primary strategy in the fight against cancer is to screen compounds that may be effective
on different types of cancer. Compounds from plants seem to be a good source. The present …

Simple Summary Breast cancer is the most commonly diagnosed and second leading cause
of cancer-related deaths in women in the United States, with hormone receptor positive …