[HTML][HTML] Gamma-aminobutyric acid and probiotics: Multiple health benefits and their future in the global functional food and nutraceuticals market
L Diez-Gutiérrez, L San Vicente, LJR Barrón… - Journal of Functional …, 2020 - Elsevier
Probiotics have attracted growing interest in recent decades due to their multiple health
benefits. The synergistic relationship between probiotics and prebiotics can enhance the …
benefits. The synergistic relationship between probiotics and prebiotics can enhance the …
GABAergic signaling by cells of the immune system: more the rule than the exception
AK Bhandage, A Barragan - Cellular and Molecular Life Sciences, 2021 - Springer
Gamma-aminobutyric acid (GABA) is best known as an essential neurotransmitter in the
evolved central nervous system (CNS) of vertebrates. However, GABA antedates the …
evolved central nervous system (CNS) of vertebrates. However, GABA antedates the …
Neuroimmune pathophysiology in asthma
GF Pavón-Romero, NH Serrano-Pérez… - Frontiers in Cell and …, 2021 - frontiersin.org
Asthma is a chronic inflammation of lower airway disease, characterized by bronchial
hyperresponsiveness. Type I hypersensitivity underlies all atopic diseases including allergic …
hyperresponsiveness. Type I hypersensitivity underlies all atopic diseases including allergic …
Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved …
DE Knutson, R Kodali, B Divović… - Journal of medicinal …, 2018 - ACS Publications
Recent reports indicate that α6β2/3γ2 GABAAR selective ligands may be important for the
treatment of trigeminal activation-related pain and neuropsychiatric disorders with sensori …
treatment of trigeminal activation-related pain and neuropsychiatric disorders with sensori …
[HTML][HTML] Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin …
A Abdelazez, H Abdelmotaal, SE Evivie… - Food Science and …, 2022 - Elsevier
The therapeutic effect of gamma-aminobutyric acid (GABA) on diabetes was spread as one
of the alarming epidemics worldwide. The study aims to investigate the function of …
of the alarming epidemics worldwide. The study aims to investigate the function of …
A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung
We describe lead compound MIDD0301 for the oral treatment of asthma based on
previously developed positive allosteric α5β3γ2 selective GABAA receptor (GABAAR) …
previously developed positive allosteric α5β3γ2 selective GABAA receptor (GABAAR) …
Design, synthesis, and biological evaluation of novel spiro imidazobenzodiazepines to identify improved inhaled bronchodilators
DA Webb, MJ Meyer, KM Medubi… - Journal of Medicinal …, 2023 - ACS Publications
Novel gamma-aminobutyric acid receptor (GABAAR) ligands structurally related to
imidazobenzodiazepine MIDD0301 were synthesized using spiro-amino acid N …
imidazobenzodiazepine MIDD0301 were synthesized using spiro-amino acid N …
[HTML][HTML] GABAA receptor subtypes regulate stress-induced colon inflammation in mice
Background & Aims Psychological stress, in early life or adulthood, is a significant risk factor
for inflammatory disorders, including inflammatory bowel diseases. However, little is known …
for inflammatory disorders, including inflammatory bowel diseases. However, little is known …
Molecular characterization of GABA-A receptor subunit diversity within major peripheral organs and their plasticity in response to early life psychosocial stress
EA Everington, AG Gibbard, JD Swinny… - Frontiers in Molecular …, 2018 - frontiersin.org
Gamma aminobutyric acid (GABA) subtype A receptors (GABAARs) are integral membrane
ion channels composed of five individual proteins or subunits. Up to 19 different GABAAR …
ion channels composed of five individual proteins or subunits. Up to 19 different GABAAR …
Gut health benefits and associated systemic effects provided by functional components from the fermentation of natural matrices
R Colucci Cante, F Nigro, F Passannanti… - … Reviews in Food …, 2024 - Wiley Online Library
Recently, the role of the gut microbiota in metabolic health, immunity, behavioral balance,
longevity, and intestine comfort has been the object of several studies from scientific …
longevity, and intestine comfort has been the object of several studies from scientific …