Squamous cell lung cancers (lung squamous cell carcinomas [LUSCs]) are associated with
high mortality and a lack of therapies specific to this disease. Although recurrent molecular …

Growing implications of glycosylation in physiological occurrences and human disease have
prompted intensive focus on revealing glycomic perturbations through absolute and relative …

Lung cancer is one of the deadliest cancers in the world. Two of the most common subtypes,
lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), have drastically …

Lung malignancies comprise lethal and aggressive tumours that remain the leading cancer-
related death cause worldwide. Regarding histological classification, lung squamous cell …

Tn is a tumor-associated carbohydrate antigen that constitutes both a diagnostic tool and an
immunotherapeutic target. It originates from interruption of the mucin O-glycosylation …

Prediction of driver genes (tumor suppressors and oncogenes) is an essential step in
understanding cancer development and discovering potential novel treatments. We recently …

Background Invasive lobular carcinoma (ILC) treatment is similar to invasive ductal
carcinoma (IDC; now invasive carcinoma-no special type, IBC-NST), based on its intrinsic …

Motivation Gene expression and regulation, a key molecular mechanism driving human
disease development, remains elusive, especially at early stages. Integrating the increasing …

MUC4, a transmembrane mucin, plays important roles in epithelial renewal and
differentiation. Recent studies suggest that MUC4 has been implicated in pancreatic cancer …

Lung cancer poses the greatest cancer-related death risk and males have poorer outcomes
than females, for unknown reasons. Patient sex is not a biological variable considered in …