A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

[HTML][HTML] The effects of intermittent fasting on brain and cognitive function

J Gudden, A Arias Vasquez, M Bloemendaal - Nutrients, 2021 - mdpi.com
The importance of diet and the gut-brain axis for brain health and cognitive function is
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …

The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases

A DeMaio, S Mehrotra, K Sambamurti… - Journal of …, 2022 - Springer
The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

The gut microbiota in multiple sclerosis: an overview of clinical trials

G Schepici, S Silvestro, P Bramanti… - Cell …, 2019 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, and degenerative disease
that affects the central nervous system. A recent study showed that interaction between the …

Role of endogenous lipopolysaccharides in neurological disorders

M Kalyan, AH Tousif, S Sonali, C Vichitra, T Sunanda… - Cells, 2022 - mdpi.com
Lipopolysaccharide (LPS) is a cell-wall immunostimulatory endotoxin component of Gram-
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …

Efficacy of sulforaphane in neurodegenerative diseases

G Schepici, P Bramanti, E Mazzon - International journal of molecular …, 2020 - mdpi.com
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. Although it
was also found in seeds and mature plants, SFN is mainly present in sprouts of many …

A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology

P Akbari, D Vuckovic, L Stefanucci, T Jiang… - Nature …, 2023 - nature.com
Blood cells contain functionally important intracellular structures, such as granules, critical to
immunity and thrombosis. Quantitative variation in these structures has not been subjected …

The impact of gut microbiota disorders on the blood–brain barrier

W Tang, H Zhu, Y Feng, R Guo… - Infection and Drug …, 2020 - Taylor & Francis
The gut microbiota is symbiotic with the human host and has been extensively studied in
recent years resulting in increasing awareness of the effects of the gut microbiota on human …

Inflammatory role of TLR-MyD88 signaling in multiple sclerosis

C Zheng, J Chen, F Chu, J Zhu, T Jin - Frontiers in molecular …, 2020 - frontiersin.org
Multiple sclerosis (MS) is a neuro-autoimmune and neurodegenerative disorder leading to
chronic inflammation, demyelination, axonal, and neuronal loss in the central nervous …

Isoflavone diet ameliorates experimental autoimmune encephalomyelitis through modulation of gut bacteria depleted in patients with multiple sclerosis

SN Jensen, NM Cady, SK Shahi, SR Peterson… - Science …, 2021 - science.org
The gut microbiota is a potential environmental factor that influences the development of
multiple sclerosis (MS). We and others have demonstrated that patients with MS and healthy …