6, 7-Coumarin-heterocyclic hybrids: a comprehensive review of their natural sources, synthetic approaches, and bioactivity

NM Zeki, YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

The role of oxidative stress in atopic dermatitis and chronic urticaria

S Galiniak, M Mołoń, M Biesiadecki, A Bożek, M Rachel - Antioxidants, 2022 - mdpi.com
Atopic dermatitis (AD) and chronic urticaria (CU) are common skin diseases with an
increasing prevalence and pathogenesis that are not fully understood. Emerging evidence …

The therapeutic potential of γ-Al2O3 nanoparticle containing 5-fluorouracil in the treatment of colorectal cancer

K Fasihi, F Amerizadeh, R Sabbaghzadeh, M Heydari… - Tissue and Cell, 2022 - Elsevier
Fluorouracil (5-FU) is being used in the treatment of several malignancies, but side effects
are often reported and include: diarrhea, vomiting, nausea, poor appetite, watery eyes, and …

Coenzyme Q10 supplementation affects cellular ionic balance: relevance to aging

P Srivastava, S Bhoumik, AK Yadawa… - … für Naturforschung C, 2024 - degruyter.com
Aging results into disruptive physiological functioning and cellular processes that affect the
composition and structure of the plasma membrane. The plasma membrane is the major …

Systemic oxidative stress and antioxidant capacity in cancer patients

M Leimkühler, AR Bourgonje, H van Goor… - Journal of …, 2020 - research.rug.nl
Various factors impact the outcome of patients with the diagnosis of cancer. Common
treatment modalities of cancer, including surgery, radiation therapy and cytostatic agents, all …

Fluorometric assessment of sulfhydryl oxidase activity: Optimization by response surface methodology

MH Hadwan, ARS Alsalman, LA Almashhedy… - Journal of …, 2022 - Springer
Sulfhydryl oxidase was studied using a spectrofluorometric assay. The current protocol
operates by using a combination of hemoglobin (HB) and hematin (HT) as a peroxidase …

[PDF][PDF] Ameliorative role of Plectranthus esculentus on 4-Vinylcyclohexene monoepoxide-induced oxidative stress in Drosophila melanogaster

O Balogun, AO Abolaji, AO Adedara… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Plectranthus esculentus is a plant used to relieve pain and digestive disorders. 4-
Vinylcyclohexene 1, 2-monoepoxide (VCM) is a toxic metabolite of 4-vinylcyclohexene. The …

Influenza ve tetanoz ile aşılanmış atlarda bazı serum oksidatif stres parametrelerindeki değişikliklerin izlenmesi

A Lüleci - 2023 - acikerisim.aksaray.edu.tr
Sunulan çalışmada, İnfluenza ve Tetanoz kombine aşısı ile aşılanmış atlarda bazı serum
oksidatif stres parametrelerindeki (Tiyol/disülfit dengesi ve Total oksidan/anti oksidan …

[PDF][PDF] Protective Effect of Astaxanthin on Histopathologic Changes Induced by Bisphenol A in the Liver of Rats

SC Karabekir, B Gultekin, IC Ayan, HB Savas, G Cuce… - 2024 - pvj.com.pk
Bisphenol A (BPA) has several potential uses, including in polycarbonate plastics and epoxy
resins, which could expose humans to it. Recognized for its hepatotoxicity and ability to …