On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …

C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at
sites of infection or inflammation. CRP is produced as a homopentameric protein, termed …

Abstract Aims Interleukin-6 (IL-6) contributes to atherosclerotic plaque destabilization and is
involved in myocardial injury during ischaemia–reperfusion. Interleukin-6 is therefore a …

Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …

ContextAlthough it has been hypothesized that hypertension is in part an inflammatory
disorder, clinical data linking inflammation with incident hypertension are scarce …

Atherosclerotic disease remains the leading cause of death in industrialized nations despite
major advances in its diagnosis, treatment, and prevention. The increasing epidemic of …

One of the major challenges of cardiovascular primary prevention approach is the absence
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …

Background—Given the central importance of nitric oxide (NO) in the development and
clinical course of cardiovascular diseases, we sought to determine whether the powerful …

and by CD40/CD40 ligand (CD40L and CD154) interactions. 18–22 Once adherent, the
monocytes transmigrate into the tunica intima, the innermost layer of the arterial wall …

Objectives: The purpose of this study was to evaluate the association between inflammation
and heart failure (HF) risk in older adults. Background: Inflammation is associated with HF …