Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae

D Pavlovic, S Pekic, M Stojanovic, V Popovic - Pituitary, 2019 - Springer
Traumatic brain injury (TBI) causes substantial neurological disabilities and mental distress.
Annual TBI incidence is in magnitude of millions, making it a global health challenge …

Blood biomarkers for mild traumatic brain injury: a selective review of unresolved issues

DB Hier, T Obafemi-Ajayi, MS Thimgan, GR Olbricht… - Biomarker …, 2021 - Springer
Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …

S100B, actor and biomarker of mild traumatic brain injury

C Oris, S Kahouadji, J Durif, D Bouvier… - International Journal of …, 2023 - mdpi.com
Mild traumatic brain injury (mTBI) accounts for approximately 80% of all TBI cases and is a
growing source of morbidity and mortality worldwide. To improve the management of …

S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of …

M Amoo, J Henry, PJ O'Halloran, P Brennan… - Neurosurgical …, 2022 - Springer
Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …

Blood-based traumatic brain injury biomarkers–Clinical utilities and regulatory pathways in the United States, Europe and Canada

KK Wang, JC Munoz Pareja, S Mondello… - Expert review of …, 2021 - Taylor & Francis
Introduction Traumatic brain injury (TBI) is a major global health issue, resulting in
debilitating consequences to families, communities, and health-care systems. Prior research …

Effects of age and time since injury on traumatic brain injury blood biomarkers: a TRACK-TBI study

RC Gardner, AM Puccio, FK Korley… - Brain …, 2023 - academic.oup.com
Older adults have the highest incidence of traumatic brain injury globally. Accurate blood-
based biomarkers are needed to assist with diagnosis of patients across the spectrum of age …

Prospective validation of the scandinavian guidelines for initial management of minimal, mild, and moderate head injuries in adults

M Minkkinen, GL Iverson, AK Kotilainen… - Journal of …, 2019 - liebertpub.com
Abstract The Scandinavian Guidelines for Initial Management of Minimal, Mild, and
Moderate Head Injuries in Adults (Scandinavian guidelines) are the first to incorporate …

Utility and effectiveness of the Scandinavian guidelines to exclude computerized tomography scanning in mild traumatic brain injury-a prospective cohort study

A Ananthaharan, G Kravdal… - BMC Emergency …, 2018 - Springer
Abstract Background In 2013 the Scandinavian Neurotrauma Committee (SNC) published
updated guidelines for the initial management of minimal, mild and moderate traumatic head …

In Vitro Detection of S100B and Severity Evaluation of Traumatic Brain Injury Based on Biomimetic Peptide‐Modified Nanochannels

W Zhang, J Zhang, Y Wang, S Wang, Y Wu, W Zhang… - Small, 2024 - Wiley Online Library
The diagnosis and evaluation of traumatic brain injury (TBI) are crucial steps toward the
treatment and prognosis of patients. A common question remains as to whether it is possible …

Blood biomarkers of mild traumatic brain injury: state of art

V Sapin, R Gaulmin, R Aubin, S Walrand, A Coste… - Neurochirurgie, 2021 - Elsevier
Background Mild traumatic brain injury (mTBI) is one of the most common causes of
emergency department visits around the world. Up to 90% of injuries are classified as mTBI …