In the last decades, evidence suggesting the direct or indirect involvement of B cells on
multiple sclerosis (MS) pathogenesis has accumulated. The increased amount of data on …

Immune thrombocytopenia (ITP) is commonly encountered in clinical practice. In 1996 the
American Society of Hematology published a landmark guidance paper designed to assist …

METHODS Patients (> 18 years of age) with previously untreated high–tumor-burden
follicular lymphoma were nonrandomly assigned to receive one of three …

Secondary hypogammaglobulinemia (SHG) is characterized by reduced immunoglobulin
levels due to acquired causes of decreased antibody production or increased antibody loss …

Previously published guidelines for the diagnosis and management of primary immune
thrombocytopenia (ITP) require updating largely due to the introduction of new classes of …

Monoclonal antibodies (mAbs) are now established as targeted therapies for malignancies,
transplant rejection, autoimmune and infectious diseases, as well as a range of new …

The article presents guidelines for the diagnosis and management of patients with primary
autoimmune haemolytic anaemia (AIHA). Topics discussed include diagnostic approach to …

Autoimmune encephalitis is one of the most rapidly growing research topics in neurology.
Along with discoveries of novel antibodies associated with the disease, clinical experience …

Background The genetic cause of primary immunodeficiency disease (PID) carries
prognostic information. Objective We conducted a whole-genome sequencing study …

Progressive multifocal leukoencephalopathy (PML) is a rare but often fatal brain disease
caused by reactivation of the polyomavirus JC. Knowledge of the characteristics of PML has …