Automated chemical oligosaccharide synthesis: novel approach to traditional challenges
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …
more accessible. However, many current methods still rely heavily upon specialized …
“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates
SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …
significant roles in a variety of vital biological processes. Access to unique and …
Stereocontrolled 1, 2-cis glycosylation as the driving force of progress in synthetic carbohydrate chemistry
SS Nigudkar, AV Demchenko - Chemical science, 2015 - pubs.rsc.org
Recent developments in stereoselective 1, 2-cis glycosylation that have emerged during the
past decade are surveyed herein. For detailed coverage of the previous achievements in the …
past decade are surveyed herein. For detailed coverage of the previous achievements in the …
Chemical synthesis of glycosaminoglycans
M Mende, C Bednarek, M Wawryszyn, P Sauter… - Chemical …, 2016 - ACS Publications
Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …
essential biological cell processes, as well as in many courses of diseases. Because of the …
Toward automated enzymatic synthesis of oligosaccharides
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …
Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research
TJ Boltje, T Buskas, GJ Boons - Nature chemistry, 2009 - nature.com
Synthetic oligosaccharides and glycoconjugates are increasingly used as probes for
biological research and as lead compounds for drug and vaccine discovery. These …
biological research and as lead compounds for drug and vaccine discovery. These …
Chemical O‐Glycosylations: An Overview
R Das, B Mukhopadhyay - ChemistryOpen, 2016 - Wiley Online Library
The development of glycobiology relies on the sources of particular oligosaccharides in their
purest forms. As the isolation of the oligosaccharide structures from natural sources is not a …
purest forms. As the isolation of the oligosaccharide structures from natural sources is not a …
Transforming glycoscience: a roadmap for the future
National Research Council, Division on Earth… - 2012 - books.google.com
A new focus on glycoscience, a field that explores the structures and functions of sugars,
promises great advances in areas as diverse as medicine, energy generation, and materials …
promises great advances in areas as diverse as medicine, energy generation, and materials …
Toward automated oligosaccharide synthesis
CH Hsu, SC Hung, CY Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …
of development in carbohydrate research is, however, relatively slow due to the problems …
Efficient platform for synthesizing comprehensive heparan sulfate oligosaccharide libraries for decoding glycosaminoglycan–protein interactions
Glycosaminoglycans (GAGs) are abundant, ubiquitous carbohydrates in biology, yet their
structural complexity has limited an understanding of their biological roles and structure …
structural complexity has limited an understanding of their biological roles and structure …