[HTML][HTML] High fat diet, gut microbiome and gastrointestinal cancer
Y Tong, H Gao, Q Qi, X Liu, J Li, J Gao, P Li, Y Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Gastrointestinal cancer is currently one of the main causes of cancer death, with a large
number of cases and a wide range of lesioned sites. A high fat diet, as a public health …
number of cases and a wide range of lesioned sites. A high fat diet, as a public health …
Mild suppression of hyperinsulinemia to treat obesity and insulin resistance
MM Page, JD Johnson - Trends in Endocrinology & Metabolism, 2018 - cell.com
Insulin plays roles in lipid uptake, lipolysis, and lipogenesis, in addition to controlling blood
glucose levels. Excessive circulating insulin is associated with adipose tissue expansion …
glucose levels. Excessive circulating insulin is associated with adipose tissue expansion …
Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation
The rising pancreatic cancer incidence due to obesity and type 2 diabetes is closely tied to
hyperinsulinemia, an independent cancer risk factor. Previous studies demonstrated …
hyperinsulinemia, an independent cancer risk factor. Previous studies demonstrated …
Defining a metabolic landscape of tumours: genome meets metabolism
C Seth Nanda, SV Venkateswaran, N Patani… - British journal of …, 2020 - nature.com
Cancer is a complex disease of multiple alterations occuring at the epigenomic, genomic,
transcriptomic, proteomic and/or metabolic levels. The contribution of genetic mutations in …
transcriptomic, proteomic and/or metabolic levels. The contribution of genetic mutations in …
Environmental risk factors for pancreatic cancer: an update
E Barone, A Corrado, F Gemignani, S Landi - Archives of Toxicology, 2016 - Springer
Pancreatic cancer (PC) is one of the most aggressive diseases. Only 10% of all PC cases
are thought to be due to genetic factors. Here, we analyzed the most recently published case …
are thought to be due to genetic factors. Here, we analyzed the most recently published case …
Glycemic status, insulin resistance, and risk of pancreatic cancer mortality in individuals with and without diabetes
METHODS: This is a cohort study of 572,021 Korean adults without cancer at baseline, who
participated in repeat screening examinations which included fasting blood glucose …
participated in repeat screening examinations which included fasting blood glucose …
Pancreatic cancer and diabetes mellitus
A Sharma, ST Chari - Current treatment options in gastroenterology, 2018 - Springer
Purpose of review The relationship between pancreatic ductal adenocarcinoma (PDAC) and
diabetes mellitus (DM) is complex. We reviewed the recent medical literature regarding the …
diabetes mellitus (DM) is complex. We reviewed the recent medical literature regarding the …
Endogenous hyperinsulinemia contributes to pancreatic cancer development
The incidence of cancers, including pancreatic ductal adenocarcinoma (PDAC), continues to
rise alongside the global obesity and diabetes epidemics. This rise suggests that factors …
rise alongside the global obesity and diabetes epidemics. This rise suggests that factors …
Targeting adipokines in obesity-related tumors
X Pu, D Chen - Frontiers in Oncology, 2021 - frontiersin.org
Obesity, a global epidemic, is an independent risk factor for the occurrence and
development of a variety of tumors, such as breast cancer, pancreatic cancer, ovarian …
development of a variety of tumors, such as breast cancer, pancreatic cancer, ovarian …
[HTML][HTML] Perioperative and survival outcomes following neoadjuvant FOLFIRINOX versus gemcitabine abraxane in patients with pancreatic adenocarcinoma
BC Chapman, A Gleisner, D Rigg… - JOP: Journal of the …, 2018 - ncbi.nlm.nih.gov
Perioperative and Survival Outcomes Following Neoadjuvant FOLFIRINOX versus
Gemcitabine Abraxane in Patients with Pancreatic Adenocarcinoma - PMC Back to Top …
Gemcitabine Abraxane in Patients with Pancreatic Adenocarcinoma - PMC Back to Top …