Endogenous Neural Stem Cell Mediated Oligodendrogenesis in the Adult Mammalian Brain
DZ Radecki, J Samanta - Cells, 2022 - mdpi.com
Oligodendrogenesis is essential for replacing worn-out oligodendrocytes, promoting myelin
plasticity, and for myelin repair following a demyelinating injury in the adult mammalian …
plasticity, and for myelin repair following a demyelinating injury in the adult mammalian …
Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping
Oxytocin (OXT) is a neuropeptide that has been associated with neurological diseases like
autism, a strong regulating activity on anxiety and stress-related behavior, physiological …
autism, a strong regulating activity on anxiety and stress-related behavior, physiological …
Safe and Effective Cynomolgus Monkey GLP—Tox Study with Repetitive Intrathecal Application of a TGFBR2 Targeting LNA-Gapmer Antisense Oligonucleotide as …
S Peters, E Wirkert, S Kuespert, R Heydn… - Pharmaceutics, 2022 - mdpi.com
The capability of the adult central nervous system to self-repair/regenerate was
demonstrated repeatedly throughout the last decades but remains in debate. Reduced …
demonstrated repeatedly throughout the last decades but remains in debate. Reduced …
Targeting TGF-ß in the Central Nervous System: Assessment of Cynomolgus Monkey—Toxicity and Pharmacokinetics for an LNA-Antisense Oligonucleotide
S Peters, E Wirkert, S Kuespert, R Heydn, S Korte… - Applied Sciences, 2022 - mdpi.com
Increasingly antisense oligonucleotides (ASOs) are developed for potential treatment of
CNS disorders, and due to the inability to cross the blood brain barrier, they require direct …
CNS disorders, and due to the inability to cross the blood brain barrier, they require direct …