Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

This review is focused on the structural and physicochemical aspects of metal cation
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …

Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Abstract G-quadruplex (G4) is a non-canonical structure that is formed in G-rich sequences
of nucleic acids. G4s play important roles in vivo, such as telomere maintenance …

Lead (Pb) is a highly toxic heavy metal of great environmental and health concerns, and
interestingly Pb 2+ has played important roles in nucleic acids chemistry. Since 2000, using …

Abstract G-quadruplex (G4) is a four-stranded helical DNA secondary structure formed by
guanine-rich sequence folding, and G4 has been computationally predicted to exist in a …

i-Motif DNA structures have previously been utilised for many different nanotechnological
applications, but all have used acidic conditions to fold the DNA. Herein we describe the use …

C-reactive protein (CRP) is a clinical biomarker for inflammatory diseases. In this work, we
present a simple and fast colorimetric method for CRP detection that employs citrate …

A “signal-on” photoelectrochemical sensing strategy for selective determination of Pb2+ is
designed on the basis of the combination of Pb2+-induced conformational conversion, the …

We demonstrate temperature-controlled encapsulation and release of the enzyme
horseradish peroxidase using a preassembled and covalently closed three-dimensional …