Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020 - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Biomaterial functionalization with triple-helical peptides for tissue engineering

JD Malcor, F Mallein-Gerin - Acta Biomaterialia, 2022 - Elsevier
In the growing field of tissue engineering, providing cells in biomaterials with the adequate
biological cues represents an increasingly important challenge. Yet, biomaterials with …

Protein-mimetic self-assembly with synthetic macromolecules

MH Barbee, ZM Wright, BP Allen, HF Taylor… - …, 2021 - ACS Publications
Protein-mimetic amphiphiles have significant promise as a platform to access the complex
functions of natural biological materials and incorporate the tunability and environmental …

Genetically encoded elastin-like polypeptide nanoparticles for drug delivery

JJ Milligan, S Saha, IC Jenkins, A Chilkoti - Current Opinion in …, 2022 - Elsevier
Highlights•Genetically engineered nanoparticles enable significant advances in drug
delivery.•Recombinant synthesis allows for creation of novel morphologies.•Self-assembly of …

Engineering the architecture of elastin‐like polypeptides: from unimers to hierarchical self‐assembly

S Saha, S Banskota, S Roberts, N Kirmani… - Advanced …, 2020 - Wiley Online Library
Well‐defined tunable nanostructures formed through the hierarchical self‐assembly of
peptide building blocks have drawn significant attention due to their potential applications in …

Controlled delivery of vancomycin from collagen-tethered peptide vehicles for the treatment of wound infections

J Hwang, H Huang, MO Sullivan… - Molecular …, 2023 - ACS Publications
Despite the great promise of antibiotic therapy in wound infections, antibiotic resistance
stemming from frequent dosing diminishes drug efficacy and contributes to recurrent …

Trends in the design and use of elastin-like recombinamers as biomaterials

A Ibáñez-Fonseca, T Flora, S Acosta… - Matrix Biology, 2019 - Elsevier
Abstract Elastin-like recombinamers (ELRs), which derive from one of the repetitive domains
found in natural elastin, have been intensively studied in the last few years from several …

Protein Vesicles with pH-Responsive Disassembly

DR Dautel, WT Heller, JA Champion - Biomacromolecules, 2022 - ACS Publications
Protein biomaterials offer several advantages over those made from other components
because their amino acid sequence can be precisely controlled with genetic engineering to …

Encoding Structure in Intrinsically Disordered Protein Biomaterials

RL Strader, Y Shmidov, A Chilkoti - Accounts of Chemical …, 2024 - ACS Publications
Conspectus In nature, proteins range from those with highly ordered secondary and tertiary
structures to those that completely lack a well-defined three-dimensional structure, termed …