Targeting the gut and tumor microbiota in cancer

EM Park, M Chelvanambi, N Bhutiani, G Kroemer… - Nature medicine, 2022 - nature.com
Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as
shaping cancer immunosurveillance and response to immunotherapy. Our understanding of …

Helicobacter pylori-induced gastric inflammation and gastric cancer

F Wang, W Meng, B Wang, L Qiao - Cancer letters, 2014 - Elsevier
Helicobacter pylori (H. pylori) infect over half of the world's population. The prevalence of H.
pylori infection and the predominant genotype of H. pylori virulence factors vary …

Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways

X Yong, B Tang, BS Li, R Xie, CJ Hu, G Luo… - Cell communication and …, 2015 - Springer
Helicobacter pylori (H. pylori) infection is strongly associated with the development of gastric
diseases but also with several extragastric diseases. The clinical outcomes caused by H …

Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma

Y Xi, Y Lin, W Guo, X Wang, H Zhao, C Miao… - … and Targeted Therapy, 2022 - nature.com
This study investigates aberrant DNA methylations as potential diagnosis and prognosis
markers for esophageal squamous-cell carcinoma (ESCC), which if diagnosed at advanced …

Pathogenesis of Helicobacter pylori Infection

S Backert, M Clyne - Helicobacter, 2011 - Wiley Online Library
Helicobacter pylori infections and clinical outcome are dependent on sophisticated
interactions between the bacteria and its host. Crucial bacterial factors associated with …

Upregulation of the long noncoding RNA FOXD2-AS1 promotes carcinogenesis by epigenetically silencing EphB3 through EZH2 and LSD1, and predicts poor …

T Xu, W Wang, P Ma, Y Shuai, K Zhao, Y Wang, W Li… - Oncogene, 2018 - nature.com
Accumulating data indicate that long noncoding RNAs (lncRNAs) serve as important
modulators in biological processes and are dysregulated in diverse tumors. The function of …

DNA methylation as a molecular biomarker in gastric cancer

T Tahara, T Arisawa - Epigenomics, 2015 - Taylor & Francis
DNA methylation plays a significant role in gastric carcinogenesis. The CpG island
methylator phenotype (CIMP) characterizes distinct subtypes of gastric cancer (GC) and the …

[HTML][HTML] Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis

MA Valenzuela, J Canales, AH Corvalán… - World journal of …, 2015 - ncbi.nlm.nih.gov
The sequence of events associated with the development of gastric cancer has been
described as “the gastric precancerous cascade”. This cascade is a dynamic process that …

[PDF][PDF] Environmental and lifestyle risk factors of gastric cancer

YY Lee, MH Derakhshan - Archives of Iranian medicine, 2013 - journalaim.com
Effective prevention and early diagnostic strategies are the most important public health
interventions in gastric cancer, which remains a common malignancy worldwide. Preventive …

A global burden of gastric cancer: the major impact of China

Y Nie, K Wu, J Yu, Q Liang, X Cai, Y Shang… - Expert review of …, 2017 - Taylor & Francis
Introduction: Gastric cancer (GC) is a highly aggressive cancer and a major cause of cancer-
related deaths worldwide. Approximately half of the world's GC cases and deaths occur in …