Background According to recent evidence, up to 40–50% of variance in autism spectrum
disorder (ASD) liability might be determined by environmental factors. In the present paper …

One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Objective To evaluate cardiovascular and metabolic features of offspring conceived by in
vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI). Design Literature review and …

DNA methylation is globally reprogrammed during mammalian preimplantation
development, which is critical for normal development. Recent reduced representation …

The correlation between epigenetics and human reproduction represents a very interesting
field of study, mainly due to the possible transgenerational effects related to epigenetic …

The once popular and then heretical idea that ancestral environment can affect the
phenotype of future generations is coming back into vogue due to advances in the field of …

BACKGROUND The advances in the world of IVF during the last decades have been rapid
and impressive and culture media play a major role in this success. Until the 1980s fertility …

Abstract Changes in epigenetic marks such as DNA methylation and histone acetylation are
associated with a broad range of disease traits, including cancer, asthma, metabolic …

Objective To describe the events associated with the blastocyst formation and implantation
that occur in embryos during preimplantation development based on the largest sample size …