Recent Insights into the Pathophysiology of Narcolepsy Type 1
Summary Narcolepsy type 1 (NT1) is a sleep-wake disorder in which people typically
experience excessive daytime sleepiness, cataplexy and other sleep-wake disturbances …
experience excessive daytime sleepiness, cataplexy and other sleep-wake disturbances …
Polygenic risk score analysis revealed shared genetic background in attention deficit hyperactivity disorder and narcolepsy
N Takahashi, T Nishimura, T Harada… - Translational …, 2020 - nature.com
Attention deficit hyperactive disorder (ADHD) is a highly heritable neurodevelopmental
disorder, and excessive daytime sleepiness is frequently observed in ADHD patients …
disorder, and excessive daytime sleepiness is frequently observed in ADHD patients …
Disrupted topological properties of structural brain networks present a glutamatergic neuropathophysiology in people with narcolepsy
G Chen, W Wang, H Wu, X Zhao, X Kang, J Ren… - Sleep, 2024 - academic.oup.com
Study Objectives Growing evidences have documented various abnormalities of the white
matter bundles in people with narcolepsy. We sought to evaluate topological properties of …
matter bundles in people with narcolepsy. We sought to evaluate topological properties of …
Resting-state brain network topological properties and the correlation with neuropsychological assessment in adolescent narcolepsy
Abstract Study Objectives To evaluate functional connectivity and topological properties of
brain networks, and to investigate the association between brain topological properties and …
brain networks, and to investigate the association between brain topological properties and …
Assessment of glymphatic function in narcolepsy using DTI-ALPS index
Introduction Sleep is a modulator of glymphatic activity which is altered in various sleep
disorders. Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness …
disorders. Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness …
Neuroimaging in narcolepsy and idiopathic hypersomnia: from neural correlates to clinical practice
Abstract Purpose of Review Clinical presentation of central hypersomnolence disorders,
including narcolepsy type 1 and 2 and idiopathic hypersomnia, is often similar, and …
including narcolepsy type 1 and 2 and idiopathic hypersomnia, is often similar, and …
Autism spectrum disorder and narcolepsy: a possible connection that deserves to be investigated
A Posar, P Visconti, V Blunda, F Pizza… - Frontiers in Psychiatry, 2020 - frontiersin.org
Narcolepsy in childhood-adolescence is characterized by a high occurrence of psychiatric
comorbidities. The most frequent psychiatric disorders reported in these patients are …
comorbidities. The most frequent psychiatric disorders reported in these patients are …
The sustained attention to response task shows lower cingulo-opercular and frontoparietal activity in people with narcolepsy type 1: an fMRI study on the neural …
JK Gool, YD van der Werf, GJ Lammers, R Fronczek - Brain sciences, 2020 - mdpi.com
Vigilance complaints often occur in people with narcolepsy type 1 and severely impair
effective daytime functioning. We tested the feasibility of a three-level sustained attention to …
effective daytime functioning. We tested the feasibility of a three-level sustained attention to …
Microstructural White Matter Abnormalities in Children and Adolescents With Narcolepsy Type 1
Abstract Background In 2010, the H1N1 Pandemrix vaccination campaign was followed by a
sudden increase in narcolepsy type 1 (NT1). We investigated the brain white matter …
sudden increase in narcolepsy type 1 (NT1). We investigated the brain white matter …
Evidence of genetic overlap between circadian preference and brain white matter microstructure
Several neuroimaging studies have reported associations between brain white matter
microstructure and chronotype. However, it is unclear whether those phenotypic …
microstructure and chronotype. However, it is unclear whether those phenotypic …