FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC
H Chi, X Gao, Z Xia, W Yu, X Yin, Y Pan… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Endometrial cancer (UCEC) is a highly heterogeneous gynecologic
malignancy that exhibits variable prognostic outcomes and responses to immunotherapy …
malignancy that exhibits variable prognostic outcomes and responses to immunotherapy …
Expediting the design, discovery and development of anticancer drugs using computational approaches
Cancer is considered as one of the world's leading causes of morbidity and mortality. Over
the past four decades, spectacular advances in molecular and cellular biology have led to …
the past four decades, spectacular advances in molecular and cellular biology have led to …
Deciphering the Molecular Landscape of the FAM72 Gene Family: Implications for Stem Cell Biology and Cancer
J Ramesh, RM Gopalakrishnan, THA Nguyen… - Neurochemistry …, 2024 - Elsevier
Family with sequence similarity 72 (FAM72) is a protein-coding gene family located on
chromosome 1 in humans, uniquely featuring four paralogs: FAM72A, FAM72B, FAM72C …
chromosome 1 in humans, uniquely featuring four paralogs: FAM72A, FAM72B, FAM72C …
Antibacterial, Antifungal, and Antioxidant Activities of Silver Nanoparticles Biosynthesized from Bauhinia tomentosa Linn
S Renganathan, S Subramaniyan, N Karunanithi… - Antioxidants, 2021 - mdpi.com
The biogenic synthesis of silver nanoparticles (AgNPs) has a wide range of applications in
the pharmaceutical industry. Here, we synthesized AgNPs using the aqueous flower extract …
the pharmaceutical industry. Here, we synthesized AgNPs using the aqueous flower extract …
Identification of mitochondrial-related prognostic biomarkers associated with primary bile acid biosynthesis and tumor microenvironment of hepatocellular carcinoma
T Zhang, Y Nie, J Gu, K Cai, X Chen, H Li… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the leading causes of tumor-associated deaths
worldwide. Despite great progress in early diagnosis and multidisciplinary tumor …
worldwide. Despite great progress in early diagnosis and multidisciplinary tumor …
Phytochemical Profiling in Conjunction with In Vitro and In Silico Studies to Identify Human α-Amylase Inhibitors in Leucaena leucocephala (Lam.) De Wit for the …
S Renganathan, S Manokaran, P Vasanthakumar… - ACS …, 2021 - ACS Publications
Bioactive constituents from natural sources are of great interest as alternatives to synthetic
compounds for the treatment of various diseases, including diabetes mellitus. In the present …
compounds for the treatment of various diseases, including diabetes mellitus. In the present …
Identification of a chemotherapeutic lead molecule for the potential disruption of the FAM72A-UNG2 interaction to interfere with genome stability, centromere formation …
Simple Summary Pivotal factors that contribute to tumorigenesis were subjected to analysis
by molecular modeling. In particular, the FAM72A-UNG2 protein–protein interaction was …
by molecular modeling. In particular, the FAM72A-UNG2 protein–protein interaction was …
FAM72, glioblastoma multiforme (GBM) and beyond
Simple Summary Glioblastoma multiforme (GBM) is a serious and aggressive cancer
disease that has not allowed scientists to rest for decades. In this review, we consider the …
disease that has not allowed scientists to rest for decades. In this review, we consider the …
[HTML][HTML] All-or-(N) One–an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci
FAM72 is a novel neuronal progenitor cell (NPC) self-renewal supporting protein expressed
under physiological conditions at low levels in other tissues. Accumulating data indicate the …
under physiological conditions at low levels in other tissues. Accumulating data indicate the …
A redox-sensitive iron-sulfur cluster in murine FAM72A controls its ability to degrade the nuclear form of uracil-DNA glycosylase
JA Stewart, AS Bhagwat - DNA repair, 2022 - Elsevier
Abstract Murine FAM72A, mFAM72A, binds the nuclear form of uracil-DNA glycosylase,
mUNG2, inhibits its activity and causes its degradation. In immunoprecipitation assays the …
mUNG2, inhibits its activity and causes its degradation. In immunoprecipitation assays the …