Runs of homozygosity: current knowledge and applications in livestock
E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
Inbreeding depression in livestock species: review and meta‐analysis
G Leroy - Animal genetics, 2014 - Wiley Online Library
Inbreeding, by virtue of its consequence on traits of interest, is a topic of major interest for
geneticists and animal breeders. Based on meta‐analysis conducted on 57 studies and …
geneticists and animal breeders. Based on meta‐analysis conducted on 57 studies and …
Inbreeding and runs of homozygosity: A possible solution to an old problem
Quantifying human, plant and livestock inbreeding has been an important goal of
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …
evolutionary biologists and agricultural scientists for nearly a century, and methods to do so …
The distribution of runs of homozygosity and selection signatures in six commercial meat sheep breeds
Domestication and the subsequent selection of animals for either economic or
morphological features can leave a variety of imprints on the genome of a population …
morphological features can leave a variety of imprints on the genome of a population …
Analysis of runs of homozygosity and their relationship with inbreeding in five cattle breeds farmed in Italy
Increased inbreeding is an inevitable consequence of selection in livestock populations. The
analysis of high‐density single nucleotide polymorphisms (SNPs) facilitates the identification …
analysis of high‐density single nucleotide polymorphisms (SNPs) facilitates the identification …
Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …
limited information on the ability of different methods to measure true inbreeding. In the …
Estimating autozygosity from high-throughput information: effects of SNP density and genotyping errors
Background Runs of homozygosity are long, uninterrupted stretches of homozygous
genotypes that enable reliable estimation of levels of inbreeding (ie, autozygosity) based on …
genotypes that enable reliable estimation of levels of inbreeding (ie, autozygosity) based on …
Estimation of inbreeding using pedigree, 50k SNP chip genotypes and full sequence data in three cattle breeds
Background Levels of inbreeding in cattle populations have increased in the past due to the
use of a limited number of bulls for artificial insemination. High levels of inbreeding lead to …
use of a limited number of bulls for artificial insemination. High levels of inbreeding lead to …
Effect of artificial selection on runs of homozygosity in US Holstein cattle
The intensive selection programs for milk made possible by mass artificial insemination
increased the similarity among the genomes of North American (NA) Holsteins tremendously …
increased the similarity among the genomes of North American (NA) Holsteins tremendously …
Next‐generation metrics for monitoring genetic erosion within populations of conservation concern
Genetic erosion is a major threat to biodiversity because it can reduce fitness and ultimately
contribute to the extinction of populations. Here, we explore the use of quantitative metrics to …
contribute to the extinction of populations. Here, we explore the use of quantitative metrics to …