The spectrum of spitz melanocytic lesions: from morphologic diagnosis to molecular classification

TW Cheng, MC Ahern, A Giubellino - Frontiers in Oncology, 2022 - frontiersin.org
Spitz tumors represent a distinct subtype of melanocytic lesions with characteristic
histopathologic features, some of which are overlapping with melanoma. More common in …

Update on melanocytic nevi in children

JV Schaffer - Clinics in dermatology, 2015 - Elsevier
A new or changing melanocytic nevus in a child or adolescent often leads to concern in
parents and physicians. To avoid undue alarm and unnecessary procedures, dermatologists …

Spitz nevi and other spitzoid neoplasms in children: overview of incidence data and diagnostic criteria

E Dika, GM Ravaioli, PA Fanti, I Neri… - Pediatric …, 2017 - Wiley Online Library
Spitz nevi are benign melanocytic neoplasms characterized by epithelioid or spindle
melanocytes or both. In some rare cases their presentation overlaps with the clinical and …

[HTML][HTML] New and evolving concepts of melanocytic nevi and melanocytomas

I Yeh - Modern Pathology, 2020 - Elsevier
In daily clinical practice melanocytic nevi are commonly encountered. Traditionally, both
benign and malignant melanocytic tumors have been sub-classified by their histopathologic …

An update on genomic aberrations in Spitz naevi and tumours

M Hagstrom, M Fumero-Velázquez, S Dhillon… - Pathology, 2023 - Elsevier
Spitz neoplasms continue to be a diagnostic challenge for dermatopathologists and are
defined by distinctive morphological and genetic features. With the recent advancements in …

Evaluation and Surgical Management of Pediatric Cutaneous Melanoma and Atypical Spitz and Non-Spitz Melanocytic Tumors (Melanocytomas): A Report From …

MR Sargen, RL Barnhill, DE Elder… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE The purpose of this study was to develop recommendations for the diagnostic
evaluation and surgical management of cutaneous melanoma (CM) and atypical Spitz …

Morphologic features in a series of 352 Spitz melanocytic proliferations help predict their oncogenic drivers

T Kervarrec, D Pissaloux, F Tirode, M Samimi… - Virchows Archiv, 2022 - Springer
Spitz nevi are indolent melanocytic tumors arising preferentially during and after childhood.
Over the last decades, recurrent oncogenic drivers, sparsely detected in melanoma, were …

[HTML][HTML] Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas

R Lazova, N Pornputtapong, R Halaban, M Bosenberg… - Modern Pathology, 2017 - Elsevier
We performed exome sequencing of 77 melanocytic specimens composed of Spitz nevi (n=
29), Spitzoid melanomas (n= 27), and benign melanocytic nevi (n= 21), and compared the …

[HTML][HTML] The morpho-molecular landscape of spitz neoplasms

CA Dal Pozzo, R Cappellesso - International Journal of Molecular …, 2022 - mdpi.com
Spitz neoplasms are a heterogeneous group of melanocytic proliferations with a great
variability in the histological characteristics and in the biological behavior. Thanks to recent …

[HTML][HTML] PTPN11 mosaicism causes a spectrum of pigmentary and vascular neurocutaneous disorders and predisposes to melanoma

S Polubothu, N Bender, S Muthiah, D Zecchin… - Journal of Investigative …, 2023 - Elsevier
Phakomatosis pigmentovascularis is a diagnosis that denotes the coexistence of pigmentary
and vascular birthmarks of specific types, accompanied by variable multisystem …