Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells
GC Baltazar, S Guha, W Lu, J Lim, K Boesze-Battaglia… - PloS one, 2012 - journals.plos.org
Lysosomal enzymes function optimally in acidic environments, and elevation of lysosomal
pH can impede their ability to degrade material delivered to lysosomes through autophagy …
pH can impede their ability to degrade material delivered to lysosomes through autophagy …