Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain

V Karri, M Schuhmacher, V Kumar - Environmental toxicology and …, 2016 - Elsevier
Human exposure to toxic heavy metals is a global challenge. Concurrent exposure of heavy
metals, such as lead (Pb), cadmium (Cd), arsenic (As) and methylmercury (MeHg) are …

Occurrence of trace metals in foodstuffs and their health impact

AA El-Kady, MA Abdel-Wahhab - Trends in food science & technology, 2018 - Elsevier
Background Unlike organic pollutants, heavy metals are not created nor are biodegradable
materials. They naturally occur in earth crust and many of them reach the environment via …

Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury

M Farina, DS Avila, JBT Da Rocha… - Neurochemistry …, 2013 - Elsevier
Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …

Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies

M Farina, JBT Rocha, M Aschner - Life sciences, 2011 - Elsevier
Neurological disorders are common, costly, and can cause enduring disability. Although
mostly unknown, a few environmental toxicants are recognized causes of neurological …

Oxidative stress in MeHg-induced neurotoxicity

M Farina, M Aschner, JBT Rocha - Toxicology and applied pharmacology, 2011 - Elsevier
Methylmercury (MeHg) is an environmental toxicant that leads to long-lasting neurological
and developmental deficits in animals and humans. Although the molecular mechanisms …

Methylmercury and brain development: A review of recent literature

AA Dos Santos, MA Hort, M Culbreth… - Journal of trace …, 2016 - Elsevier
Methylmercury (MeHg) is a potent environmental pollutant, which elicits significant toxicity in
humans. The central nervous system (CNS) is the primary target of toxicity, and is …

Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay

M Farina, M Aschner - Biochimica et Biophysica Acta (BBA)-General …, 2019 - Elsevier
Methylmercury (MeHg) is a toxic chemical compound naturally produced mainly in the
aquatic environment through the methylation of inorganic mercury catalyzed by aquatic …

[HTML][HTML] Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase

JL Franco, T Posser, PR Dunkley, PW Dickson… - Free Radical Biology …, 2009 - Elsevier
In this study, we investigated the involvement of glutathione peroxidase—GPx (EC 1.11. 1.9)
in methylmercury (MeHg)-induced toxicity using three models:(a) in mouse brain after …

[HTML][HTML] Neuroprotective potency of some spice herbs, a literature review

MR Khazdair, A Anaeigoudari, M Hashemzehi… - Journal of traditional and …, 2019 - Elsevier
In recent years, growing attention has been given to traditional medicine. In traditional
medicine a large number of plants have been used to cure neurodegenerative diseases …

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity

M Aschner, T Syversen, DO Souza… - Brazilian Journal of …, 2007 - SciELO Brasil
This review addresses the mechanisms of methylmercury (MeHg)-induced neurotoxicity,
specifically examining the role of oxidative stress in mediating neuronal damage. A number …