Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association

EA Amsterdam, JD Kirk, DA Bluemke, D Diercks… - Circulation, 2010 - Am Heart Assoc
The management of low-risk patients presenting to emergency departments is a common
and challenging clinical problem entailing 8 million emergency department visits annually …

Myeloperoxidase: a useful biomarker for cardiovascular disease risk stratification?

RK Schindhelm, LP van der Zwan, T Teerlink… - Clinical …, 2009 - academic.oup.com
Background: Inflammation and oxidative stress are associated with atherosclerosis.
Myeloperoxidase (MPO) is linked to both inflammation and oxidative stress by its location in …

Quantitative and ultrasensitive detection of multiplex cardiac biomarkers in lateral flow assay with core-shell SERS nanotags

D Zhang, L Huang, B Liu, H Ni, L Sun, E Su… - Biosensors and …, 2018 - Elsevier
Rapid and sensitive quantification of multiplex proteins in a wide concentration range is
challenging in high throughput analysis. Herein, we proposed a lateral flow assay (LFA) …

Early diagnosis of myocardial infarction with sensitive cardiac troponin assays

T Reichlin, W Hochholzer, S Bassetti… - New England journal …, 2009 - Mass Medical Soc
Background The rapid and reliable diagnosis of acute myocardial infarction is a major unmet
clinical need. Methods We conducted a multicenter study to examine the diagnostic …

The history of matrix metalloproteinases: milestones, myths, and misperceptions

RP Iyer, NL Patterson, GB Fields… - American Journal of …, 2012 - journals.physiology.org
Since the discovery of tadpole collagenase in 1962, the matrix metalloproteinase (MMP)
family has emerged as a significant proteinase group with recognized effects on the …

Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study

PN Floriano, N Christodoulides, CS Miller… - Clinical …, 2009 - academic.oup.com
Background: For adults with chest pain, the electrocardiogram (ECG) and measures of
serum biomarkers are used to screen and diagnose myocardial necrosis. These …

Heart-type fatty acid-binding protein predicts long-term mortality and re-infarction in consecutive patients with suspected acute coronary syndrome who are troponin …

K Viswanathan, N Kilcullen, C Morrell… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to establish the prognostic value of measuring
heart fatty acid-binding protein (H-FABP) in patients with suspected acute coronary …

Emergency department and office-based evaluation of patients with chest pain

MC Kontos, DB Diercks, JD Kirk - Mayo Clinic Proceedings, 2010 - Elsevier
The management of patients with chest pain is a common and challenging clinical problem.
Although most of these patients do not have a life-threatening condition, the clinician must …

Prospective evaluation of the prognostic implications of improved assay performance with a sensitive assay for cardiac troponin I

M Bonaca, B Scirica, M Sabatine, A Dalby… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to investigate the prognostic implications of low-
level increases in cardiac troponin I (cTnI) using a current-generation sensitive assay in …

Critical appraisal of inflammatory markers in cardiovascular risk stratification

M Krintus, M Kozinski, J Kubica… - Critical reviews in …, 2014 - Taylor & Francis
Despite great progress in prevention strategies, pharmacotherapy and interventional
treatment of coronary artery disease (CAD), cardiovascular events still constitute the leading …