Mesenchymal stem cell-derived exosomes: applications in regenerative medicine

MD Hade, CN Suire, Z Suo - Cells, 2021 - mdpi.com
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Umbilical cord-derived mesenchymal stem cell-derived exosomes combined pluronic F127 hydrogel promote chronic diabetic wound healing and complete skin …

J Yang, Z Chen, D Pan, H Li, J Shen - International journal of …, 2020 - Taylor & Francis
Purpose Chronic refractory wounds are a multifactorial comorbidity of diabetes mellitus with
the characteristic of impaired vascular networks. Currently, there is a lack of effective …

Understanding chronic venous disease: a critical overview of its pathophysiology and medical management

MA Ortega, O Fraile-Martínez… - Journal of clinical …, 2021 - mdpi.com
Chronic venous disease (CVD) is a multifactorial condition affecting an important
percentage of the global population. It ranges from mild clinical signs, such as …

A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing

J Zhang, Y Zheng, J Lee, J Hua, S Li… - Nature …, 2021 - nature.com
Effective healing of skin wounds is essential for our survival. Although skin has strong
regenerative potential, dysfunctional and disfiguring scars can result from aberrant wound …

Wound dressings functionalized with silver nanoparticles: promises and pitfalls

K Kalantari, E Mostafavi, AM Afifi, Z Izadiyan… - Nanoscale, 2020 - pubs.rsc.org
Infections are the main reason why most people die from burns and diabetic wounds. The
clinical challenge for treating wound infections through traditional antibiotics has been …

Wound repair and regeneration: mechanisms, signaling, and translation

SA Eming, P Martin, M Tomic-Canic - Science translational medicine, 2014 - science.org
The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

Cellular and molecular mechanisms of repair in acute and chronic wound healing

P Martin, R Nunan - British Journal of Dermatology, 2015 - academic.oup.com
A considerable understanding of the fundamental cellular and molecular mechanisms
underpinning healthy acute wound healing has been gleaned from studying various animal …

Nanotechnology-driven therapeutic interventions in wound healing: potential uses and applications

S Hamdan, I Pastar, S Drakulich, E Dikici… - ACS central …, 2017 - ACS Publications
The chronic nature and associated complications of nonhealing wounds have led to the
emergence of nanotechnology-based therapies that aim at facilitating the healing process …

Transforming growth factor beta (TGF‐β) isoforms in wound healing and fibrosis

MK Lichtman, M Otero‐Vinas… - Wound Repair and …, 2016 - Wiley Online Library
Scar formation, with persistent alteration of the normal tissue structure, is an undesirable and
significant result of both wound healing and fibrosing disorders. There are few strategies to …