Optimization methods in chromatography and capillary electrophoresis

AM Siouffi, R Phan-Tan-Luu - Journal of Chromatography A, 2000 - Elsevier
Many methods have been developed in order to optimize the parameters of interest in either
chromatography or capillary electrophoresis. In chemometric approaches experimental …

Retention index in temperature-programmed gas chromatography

FR Gonzalez, AM Nardillo - Journal of Chromatography A, 1999 - Elsevier
A persistent feature in the development of temperature-programmed gas chromatography
(TPGC) has been the search of a retention index IT, defined as a relationship between the …

Foundations of retention in partition chromatography

CF Poole, SK Poole - Journal of Chromatography A, 2009 - Elsevier
The connection between the observable output in column chromatography (retention time,
retention volume, retention factor, separation factor, etc.) and system properties (hold-up …

Relation between characteristic temperature and elution temperature in temperature programmed gas chromatography-part I: Influence of initial temperature and …

T Brehmer, P Boeker, M Wüst, J Leppert - Journal of Chromatography A, 2023 - Elsevier
The development of new analytical methods can save resources, time and costs if there are
prediction tools like computer simulation which support the optimization process. In GC the …

Simulation of spatial thermal gradient gas chromatography

J Leppert, PJ Müller, MD Chopra, LM Blumberg… - … of Chromatography A, 2020 - Elsevier
A model to simulate the gas chromatographic separation in the presence of a spatial thermal
gradient is presented. This model is developed from existing models for the prediction of …

Estimation of retention parameters from temperature programmed gas chromatography

J Leppert, T Brehmer, M Wüst, P Boeker - Journal of Chromatography A, 2023 - Elsevier
A fast and reliable method is presented to evaluate retention parameters of the distribution-
centric 3-parameter model from temperature programed gas chromatographic …

Top-down approach to retention time prediction in comprehensive two-dimensional gas chromatography–mass spectrometry

M Gaida, FA Franchina, PH Stefanuto… - Analytical …, 2022 - ACS Publications
In this contribution, we describe a novel modeling approach to predicting retention times (tr)
in comprehensive two-dimensional gas chromatography coupled to time-of-flight mass …

Comprehensive three-dimensional gas chromatography with time-of-flight mass spectrometry

NE Watson, HD Bahaghighat, K Cui… - Analytical …, 2017 - ACS Publications
Development of comprehensive, three-dimensional (3D) gas chromatography with time-of-
flight mass spectrometric detection (GC3/TOFMS) is described. This instrument provides four …

Stationary-phase optimized selectivity liquid chromatography: development of a linear gradient prediction algorithm

M De Beer, F Lynen, K Chen, P Ferguson… - Analytical …, 2010 - ACS Publications
Stationary-phase optimized selectivity liquid chromatography (SOS-LC) is a tool in reversed-
phase LC (RP-LC) to optimize the selectivity for a given separation by combining stationary …

Retention models for programmed gas chromatography

G Castello, P Moretti, S Vezzani - Journal of Chromatography A, 2009 - Elsevier
The models proposed by many authors for the prediction of retention times and
temperatures, peak widths, retention indices and separation numbers in programmed …