[HTML][HTML] Circadian rhythm disruption and mental health
Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids
Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
Timing of light exposure affects mood and brain circuits
TA Bedrosian, RJ Nelson - Translational psychiatry, 2017 - nature.com
Temporal organization of physiology is critical for human health. In the past, humans
experienced predictable periods of daily light and dark driven by the solar day, which …
experienced predictable periods of daily light and dark driven by the solar day, which …
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …
How might circadian rhythms control mood? Let me count the ways...
CA McClung - Biological psychiatry, 2013 - Elsevier
Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …
been many hypotheses put forth over the years to explain the development of major …
Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis
T Ishii, E Warabi, GE Mann - Free Radical Biology and Medicine, 2019 - Elsevier
Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …
[HTML][HTML] Identification of a circadian output circuit for rest: activity rhythms in Drosophila
DJ Cavanaugh, JD Geratowski, JRA Wooltorton… - Cell, 2014 - cell.com
Though much is known about the cellular and molecular components of the circadian clock,
output pathways that couple clock cells to overt behaviors have not been identified. We …
output pathways that couple clock cells to overt behaviors have not been identified. We …
[HTML][HTML] Advances in understanding the peripheral circadian clocks
J Richards, ML Gumz - The FASEB Journal, 2012 - ncbi.nlm.nih.gov
In the past decade, it has become increasingly evident that the circadian clock system plays
an important role in many physiological processes. The circadian clock can be divided into 2 …
an important role in many physiological processes. The circadian clock can be divided into 2 …
The effects of shift work on physical and mental health
M Vogel, T Braungardt, W Meyer… - Journal of neural …, 2012 - Springer
Occupational engagement is a pre-requisite for continuous income opportunities. Among the
changing social circumstances work-related conditions play an increasingly eminent role in …
changing social circumstances work-related conditions play an increasingly eminent role in …
Circadian rhythms in the blood–brain barrier: impact on neurological disorders and stress responses
N Schurhoff, M Toborek - Molecular brain, 2023 - Springer
Circadian disruption has become more prevalent in society due to the increase in shift work,
sleep disruption, blue light exposure, and travel via different time zones. The circadian …
sleep disruption, blue light exposure, and travel via different time zones. The circadian …