[HTML][HTML] Circadian rhythm disruption and mental health

WH Walker, JC Walton, AC DeVries… - Translational psychiatry, 2020 - nature.com
Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …

The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids

H Oster, E Challet, V Ott, E Arvat, ER de Kloet… - Endocrine …, 2017 - academic.oup.com
Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Timing of light exposure affects mood and brain circuits

TA Bedrosian, RJ Nelson - Translational psychiatry, 2017 - nature.com
Temporal organization of physiology is critical for human health. In the past, humans
experienced predictable periods of daily light and dark driven by the solar day, which …

Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

How might circadian rhythms control mood? Let me count the ways...

CA McClung - Biological psychiatry, 2013 - Elsevier
Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …

Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis

T Ishii, E Warabi, GE Mann - Free Radical Biology and Medicine, 2019 - Elsevier
Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …

[HTML][HTML] Identification of a circadian output circuit for rest: activity rhythms in Drosophila

DJ Cavanaugh, JD Geratowski, JRA Wooltorton… - Cell, 2014 - cell.com
Though much is known about the cellular and molecular components of the circadian clock,
output pathways that couple clock cells to overt behaviors have not been identified. We …

[HTML][HTML] Advances in understanding the peripheral circadian clocks

J Richards, ML Gumz - The FASEB Journal, 2012 - ncbi.nlm.nih.gov
In the past decade, it has become increasingly evident that the circadian clock system plays
an important role in many physiological processes. The circadian clock can be divided into 2 …

The effects of shift work on physical and mental health

M Vogel, T Braungardt, W Meyer… - Journal of neural …, 2012 - Springer
Occupational engagement is a pre-requisite for continuous income opportunities. Among the
changing social circumstances work-related conditions play an increasingly eminent role in …

Circadian rhythms in the blood–brain barrier: impact on neurological disorders and stress responses

N Schurhoff, M Toborek - Molecular brain, 2023 - Springer
Circadian disruption has become more prevalent in society due to the increase in shift work,
sleep disruption, blue light exposure, and travel via different time zones. The circadian …