[HTML][HTML] Interaction of microglia and astrocytes in the neurovascular unit

L Liu, J Liu, J Bao, Q Bai, G Wang - Frontiers in immunology, 2020 - frontiersin.org
The interaction between microglia and astrocytes significantly influences neuroinflammation.
Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain …

[HTML][HTML] Astrocyte–neuron networks: a multilane highway of signaling for homeostatic brain function

S Mederos, C González-Arias, G Perea - Frontiers in synaptic …, 2018 - frontiersin.org
Research on glial cells over the past 30 years has confirmed the critical role of astrocytes in
pathophysiological brain states. However, most of our knowledge about astrocyte …

An emerging role of astrocytes in aging/neuroinflammation and gut-brain axis with consequences on sleep and sleep disorders

SV Gudkov, DE Burmistrov, EV Kondakova… - Ageing Research …, 2023 - Elsevier
Understanding the role of astrocytes in the central nervous system has changed dramatically
over the last decade. The accumulating findings indicate that glial cells are involved not only …

[HTML][HTML] Interstitial ions: A key regulator of state-dependent neural activity?

R Rasmussen, J O'Donnell, F Ding… - Progress in …, 2020 - Elsevier
Throughout the nervous system, ion gradients drive fundamental processes. Yet, the roles of
interstitial ions in brain functioning is largely forgotten. Emerging literature is now revitalizing …

Calcium signaling in neuroglia

D Lim, A Semyanov, A Genazzani… - International review of cell …, 2021 - Elsevier
Glial cells exploit calcium (Ca 2+) signals to perceive the information about the activity of the
nervous tissue and the tissue environment to translate this information into an array of …

Metabolic compartmentalization between astroglia and neurons in physiological and pathophysiological conditions of the neurovascular unit

S Takahashi - Neuropathology, 2020 - Wiley Online Library
Astroglia or astrocytes, the most abundant cells in the brain, are interposed between
neuronal synapses and microvasculature in the brain gray matter. They play a pivotal role in …

Glial function (and dysfunction) in the normal & ischemic brain

SD Magaki, CK Williams, HV Vinters - Neuropharmacology, 2018 - Elsevier
Astrocytes are the most abundant cell type in the central nervous system (CNS). Once
considered to be of fairly homogeneous phenotype throughout the brain and spinal cord …

[HTML][HTML] Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus

A Popov, P Denisov, M Bychkov, A Brazhe… - Cell death & …, 2020 - nature.com
Calorie-restricted (CR) diet has multiple beneficial effects on brain function. Here we report
morphological and functional changes in hippocampal astrocytes in 3-months-old mice …

[HTML][HTML] Astrocyte networks as therapeutic targets in glaucomatous neurodegeneration

AM Boal, ML Risner, ML Cooper, LK Wareham… - Cells, 2021 - mdpi.com
Astrocytes are intimately involved in the response to neurodegenerative stress and have
become an attractive target for the development of neuroprotective therapies. However …

[HTML][HTML] Interleukin-1β drives cellular senescence of rat astrocytes induced by oligomerized amyloid β peptide and oxidative stress

D Shang, Y Hong, W Xie, Z Tu, J Xu - Frontiers in Neurology, 2020 - frontiersin.org
Background: Alzheimer's disease (AD) is the leading cause of dementia. With no reliable
treatment that delays or reverses the progress of AD, effective medical drugs, and …