Liquid biopsies: the future of cancer early detection

S Connal, JM Cameron, A Sala, PM Brennan… - Journal of translational …, 2023 - Springer
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale
causing emotional, physical, and financial strains on individuals, families, and health care …

Liquid biopsies: applications for cancer diagnosis and monitoring

I Martins, IP Ribeiro, J Jorge, AC Gonçalves… - Genes, 2021 - mdpi.com
The minimally—or non-invasive detection of circulating tumor-derived components in
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …

Detection and localization of early-and late-stage cancers using platelet RNA

S GJG, M Arkani, E Post, M Antunes-Ferreira… - Cancer Cell, 2022 - cell.com
Cancer patients benefit from early tumor detection since treatment outcomes are more
favorable for less advanced cancers. Platelets are involved in cancer progression and are …

Serum extracellular vesicle-derived circHIPK3 and circSMARCA5 are two novel diagnostic biomarkers for glioblastoma multiforme

M Stella, L Falzone, A Caponnetto, G Gattuso… - Pharmaceuticals, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the most frequent and deadly human brain cancer. Early
diagnosis through non-invasive biomarkers may render GBM more easily treatable …

Liquid biopsy in glioblastoma management: from current research to future perspectives

L Gatto, E Franceschi, V Di Nunno, A Tosoni… - The …, 2021 - academic.oup.com
Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …

Advantages and challenges of using ctDNA NGS to assess the presence of minimal residual disease (MRD) in solid tumors

L Larribère, UM Martens - Cancers, 2021 - mdpi.com
Simple Summary Minimal residual disease (MRD) represents a status of the disease which
is assumed to still be present in the body until it is clinically observed by radiology. At this …

The analysis of platelet-derived circRNA repertoire as potential diagnostic biomarker for non-small cell lung cancer

S D'ambrosi, A Visser, M Antunes-Ferreira, A Poutsma… - Cancers, 2021 - mdpi.com
Simple Summary Interaction between blood platelets and cancer cells play an important role
in various steps of cancer development and progression. These interactions lead to changes …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Circulating platelets as liquid biopsy sources for cancer detection

M Antunes‐Ferreira, D Koppers‐Lalic… - Molecular …, 2021 - Wiley Online Library
Nucleic acids and proteins are shed into the bloodstream by tumor cells and can be
exploited as biomarkers for the detection of cancer. In addition, cancer detection biomarkers …

Blood-based biomarkers for glioma in the context of gliomagenesis: a systematic review

H Ali, R Harting, R de Vries, M Ali, T Wurdinger… - Frontiers in …, 2021 - frontiersin.org
Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …