Individuals infected with prions succumb to brain damage, and prion infections continue to
be inexorably lethal. However, many crucial steps in prion pathogenesis occur in lymphatic …

Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal protein-
misfolding neurodegenerative diseases. TSEs have been described in several species …

Human milk oligosaccharides (HMOs) are unique components of human breast milk. Their
large-scale production by fermentation allows infant formulas to be fortified with HMOs, but …

Prion diseases are sub-acute neurodegenerative diseases that affect humans and some
domestic and free-ranging animals. Infectious prion agents are considered to comprise …

Transmissible spongiform encephalopaties (TSEs) are fatal neurodegenerative diseases
characterized by the aggregation and accumulation of the misfolded prion protein in the …

Chronic wasting disease is a progressively fatal, horizontally transmissible prion disease
affecting several members of the cervid species. Conventional diagnosis relies on ELISA or …

In sheep, scrapie is a fatal neurologic disease that is caused by a misfolded protein called a
prion (designated PrP Sc). The normal cellular prion protein (PrP C) is encoded by an …

The transmission of chronic wasting disease (CWD) has largely been attributed to contact
with infectious prions shed in excretions (saliva, urine, feces, blood) by direct animal-to …

To assess the effectiveness of the strategies implemented in the European Union (EU) to
control Classical scrapie (CS), epidemiological data have been compared in the context of …

Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders
that affect several animal species. The causative agent, prion, is a misfolded isoform of …