[HTML][HTML] Bacterial involvement in progression and metastasis of colorectal neoplasia
KD Seely, AD Morgan, LD Hagenstein, GM Florey… - Cancers, 2022 - mdpi.com
Simple Summary Increasing evidence suggests that bacterial infection not only promotes
carcinogenesis in primary colorectal cancer, but also affects metastatic progression and …
carcinogenesis in primary colorectal cancer, but also affects metastatic progression and …
Computational screening and MM/GBSA-based MD simulation studies reveal the high binding potential of FDA-approved drugs against Cutibacterium acnes …
Cutibacterium acnes is an opportunistic pathogen linked with acne vulgaris, affecting 80–
90% of teenagers globally. On the leukocyte (WBCs) cell surface, the cell wall anchored …
90% of teenagers globally. On the leukocyte (WBCs) cell surface, the cell wall anchored …
[HTML][HTML] Structural informatics approach for designing an epitope-based vaccine against the brain-eating Naegleria fowleri
A Sarfraz, TU Wara, Sheheryar, K Chen… - Frontiers in …, 2023 - frontiersin.org
Primary Amoebic Meningoencephalitis (PAM), a severe lethal brain disease, is caused by a
parasite, Naegleria fowleri, also known as the “brain-eating amoeba”. The chances of a …
parasite, Naegleria fowleri, also known as the “brain-eating amoeba”. The chances of a …
Cytotoxic Activity of Phytoconstituents Isolated from Monotheca buxifolia against Hepatocellular Carcinoma Cell Line HepG2: In Vitro and Molecular Docking Studies
Natural products and conventional chemotherapeutic drugs are believed to enhance
anticancer treatment efficacy while lowering toxicity. The current study investigates the …
anticancer treatment efficacy while lowering toxicity. The current study investigates the …
[HTML][HTML] Identification of a Novel Therapeutic Target against XDR Salmonella Typhi H58 Using Genomics Driven Approach Followed Up by Natural Products Virtual …
Typhoid fever is caused by a pathogenic, rod-shaped, flagellated, and Gram-negative
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …
[HTML][HTML] In Silico Core Proteomics and Molecular Docking Approaches for the Identification of Novel Inhibitors against Streptococcus pyogenes
Streptococcus pyogenes is a significant pathogen that causes skin and upper respiratory
tract infections and non-suppurative complications, such as acute rheumatic fever and post …
tract infections and non-suppurative complications, such as acute rheumatic fever and post …
[HTML][HTML] In-silico drug design for the novel Karachi-NF001 strain of brain-eating amoeba: Naegleria fowleri
Naegleria fowleri (N. fowleri) is a free-living thermophilic amoeba of fresh water and soil.
The amoeba primarily feeds on bacteria but can be transmitted to humans upon contact with …
The amoeba primarily feeds on bacteria but can be transmitted to humans upon contact with …
Deciphering the Immunogenicity of Monkeypox Proteins for Designing the Potential mRNA Vaccine
The Monkeypox virus (MPXV), an orthopox virus, is responsible for monkeypox in humans, a
zoonotic disease similar to smallpox. This infection first appeared in the 1970s in humans …
zoonotic disease similar to smallpox. This infection first appeared in the 1970s in humans …
Decrypting the multi-genome data for chimeric vaccine designing against the antibiotic resistant Yersinia pestis
A Sarfraz, SQUA Fatima, M Shehroz, I Ahmad… - International …, 2024 - Elsevier
Yersinia pestis, the causative agent of plague, is a gram-negative bacterium that can be fatal
if not treated properly. Three types of plague are currently known: bubonic, septicemic, and …
if not treated properly. Three types of plague are currently known: bubonic, septicemic, and …
[HTML][HTML] Potential Therapeutic Candidates against Chlamydia pneumonia Discovered and Developed In Silico Using Core Proteomics and Molecular Docking and …
RH Kadi, KA Altammar, MM Hassan, AF Shater… - International Journal of …, 2022 - mdpi.com
Chlamydia pneumonia, a species of the family Chlamydiacea, is a leading cause of
pneumonia. Failure to eradicate C. pneumoniae can lead to chronic infection, which is why it …
pneumonia. Failure to eradicate C. pneumoniae can lead to chronic infection, which is why it …