Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Mitochondria are the main source of reactive oxygen species (ROS) in cells. Early studies
have shown that mitochondrial reactive oxygen species (mROS) are related to the …

A family of facilitative glucose transporters (GLUTs) is involved in regulating tissue-specific
glucose uptake and metabolism in the liver, skeletal muscle, and adipose tissue to ensure …

The pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P),
produces NADPH and ribose 5-phosphate (R5P), and shunts carbons back to the glycolytic …

Myricetin (MYR) is a flavonoid compound widely found in many natural plants including
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …

Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as
frequent in patients with diabetes compared with those who do not have diabetes. Moreover …

The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

Myocardial ischemic disease affects the prognosis in perioperative patients. Diabetes can
aggravate myocardial injury. The purpose of this research is to investigate the effect of …

Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …