During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

YAP/TAZ is a master regulator of mechanotransduction whose functions rely on
translocation from the cytoplasm to the nucleus in response to diverse physical cues …

Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Recent evidence has shown that, in addition to rigidity, the viscous response of the
extracellular matrix (ECM) significantly affects the behavior and function of cells. However …

The formation and recovery of gaps in the vascular endothelium governs a wide range of
physiological and pathological phenomena, from angiogenesis to tumor cell extravasation …

There is growing appreciation of the importance of the mechanical properties of the tumor
microenvironment on disease progression. However, the role of extracellular matrix (ECM) …

Biomaterials engineered with specific bioactive ligands, tunable mechanical properties and
complex architecture have emerged as powerful tools to probe cell sensing and response to …

The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

Dynamic hydrogels cross-linked by weak and reversible physical interactions enhance the 3-
dimensional (3D) spreading and mechanosensing abilities of encapsulated cells in a matrix …