Genetics of Alzheimer disease
LM Bekris, CE Yu, TD Bird… - Journal of geriatric …, 2010 - journals.sagepub.com
Alzheimer disease (AD) is the most common causes of neurodegenerative disorder in the
elderly individuals. Clinically, patients initially present with short-term memory loss …
elderly individuals. Clinically, patients initially present with short-term memory loss …
[HTML][HTML] Genetic aspects of Alzheimer disease
TD Bird - Genetics in Medicine, 2008 - Elsevier
Alzheimer disease is the most common cause of dementia and represents a major public
health problem. The neuropathologic findings of amyloid-β plaques and tau containing …
health problem. The neuropathologic findings of amyloid-β plaques and tau containing …
[HTML][HTML] Linguistic markers predict onset of Alzheimer's disease
Background The aim of this study is to use classification methods to predict future onset of
Alzheimer's disease in cognitively normal subjects through automated linguistic analysis …
Alzheimer's disease in cognitively normal subjects through automated linguistic analysis …
Risk of dementia among white and African American relatives of patients with Alzheimer disease
RC Green, LA Cupples, R Go, KS Benke, T Edeki… - Jama, 2002 - jamanetwork.com
ContextEvidence exists that the incidence of Alzheimer disease (AD), as well as risk
attributable to specific genetic factors such as apolipoprotein E (APOE) genotype, may vary …
attributable to specific genetic factors such as apolipoprotein E (APOE) genotype, may vary …
Cholinergic markers in elderly patients with early signs of Alzheimer disease
ContextA central tenet of Alzheimer disease (AD) is the loss of cortical cholinergic function
and cholinergic markers in postmortem brain specimens. Whether these profound deficits in …
and cholinergic markers in postmortem brain specimens. Whether these profound deficits in …
Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?
NT Lautenschlager, LA Cupples, VS Rao… - Neurology, 1996 - AAN Enterprises
Article abstract-Despite recent advances in the molecular genetics of Alzheimer's disease
(AD), several fundamental questions concerning risk of illness are unresolved, namely, if …
(AD), several fundamental questions concerning risk of illness are unresolved, namely, if …
Epidemiology of dementia and Alzheimer's disease
HC Hendrie - The American Journal of Geriatric Psychiatry, 1998 - Elsevier
The prevalence of dementia in subjects 65 years and older in North America is
approximately 6%–10%, with Alzheimer's disease (AD) accounting for two-thirds of these …
approximately 6%–10%, with Alzheimer's disease (AD) accounting for two-thirds of these …
[HTML][HTML] Alzheimer disease overview
TD Bird - GeneReviews®[Internet], 2018 - ncbi.nlm.nih.gov
Alzheimer Disease Overview - GeneReviews® - NCBI Bookshelf US flag An official website of
the United States government Here's how you know NIH NLM Logo Access keys NCBI …
the United States government Here's how you know NIH NLM Logo Access keys NCBI …
Molecular genetics of Alzheimer's disease
PH St George-Hyslop - Biological psychiatry, 2000 - Elsevier
Application of genetic paradigms to Alzheimer's disease (AD) has led to confirmation that
genetic factors play a role in this disease. Additionally, researchers now understand that AD …
genetic factors play a role in this disease. Additionally, researchers now understand that AD …
Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease
RE Davis, S Miller, C Herrnstadt… - Proceedings of the …, 1997 - National Acad Sciences
Mounting evidence suggests that defects in energy metabolism contribute to the
pathogenesis of Alzheimer disease (AD). Cytochrome c oxidase (CO) is kinetically …
pathogenesis of Alzheimer disease (AD). Cytochrome c oxidase (CO) is kinetically …