[HTML][HTML] The therapeutic effect of resveratrol: Focusing on the Nrf2 signaling pathway

T Farkhondeh, SL Folgado… - Biomedicine & …, 2020 - Elsevier
Resveratrol is a natural polyphenol derived from grapes, berries, red wine, peanuts amongst
other fruits and nuts. Beneficial effects such as anti-inflammatory, antioxidant …

NRF2 as a therapeutic target in neurodegenerative diseases

MS Brandes, NE Gray - ASN neuro, 2020 - journals.sagepub.com
Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …

Phenylpropanoids and its derivatives: biological activities and its role in food, pharmaceutical and cosmetic industries

Neelam, A Khatkar, KK Sharma - Critical Reviews in Food Science …, 2020 - Taylor & Francis
Phenylpropanoids and their derivatives are plant secondary metabolites widely present in
fruits, vegetables, cereal grains, beverages, spices and herbs. They are known to have …

Oxidative stress, NF-κb-mediated inflammation and apoptosis in the testes of streptozotocin–induced diabetic rats: Combined protective effects of malaysian propolis …

VU Nna, AB Abu Bakar, A Ahmad, CO Eleazu… - Antioxidants, 2019 - mdpi.com
Oxidative stress, inflammation and apoptosis are major complications that trigger organ
failure in diabetes mellitus (DM), and are proven to adversely affect the male reproductive …

[HTML][HTML] Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: a mechanism review

ZY Wang, J Liu, Z Zhu, CF Su… - Biomedicine & …, 2021 - Elsevier
Neurodegenerative diseases (NDs) are common chronic diseases related to progressive
damage of the nervous system. Globally, the number of people with an ND is dramatically …

Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse …

Y Zhang, Q Wu, L Zhang, Q Wang, Z Yang, J Liu… - Pharmacological …, 2019 - Elsevier
The human A53T mutant of α-synuclein tends to aggregate and leads to neurotoxicity in
familial Parkinson's disease (PD). The aggregation of α-synuclein is also found in sporadic …

Flavonoids as a natural enhancer of neuroplasticity—An overview of the mechanism of neurorestorative action

N Cichon, J Saluk-Bijak, L Gorniak, L Przyslo, M Bijak - Antioxidants, 2020 - mdpi.com
Neuroplasticity is a complex physiological process occurring in the brain for its entire life.
However, it is of particular importance in the case of central nervous system (CNS) …

Merging the multi-target effects of phytochemicals in neurodegeneration: From oxidative stress to protein aggregation and inflammation

F Limanaqi, F Biagioni, F Mastroiacovo, M Polzella… - Antioxidants, 2020 - mdpi.com
Wide experimental evidence has been provided in the last decade concerning the
neuroprotective effects of phytochemicals in a variety of neurodegenerative disorders …

[HTML][HTML] Recent advances in understanding dominant spinocerebellar ataxias from clinical and genetic points of view

G Coarelli, A Brice, A Durr - F1000Research, 2018 - ncbi.nlm.nih.gov
Recent advances in understanding dominant spinocerebellar ataxias from clinical and
genetic points of view - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Consensus paper: strengths and weaknesses of animal models of spinocerebellar ataxias and their clinical implications

J Cendelin, M Cvetanovic, M Gandelman, H Hirai… - The Cerebellum, 2022 - Springer
Spinocerebellar ataxias (SCAs) represent a large group of hereditary degenerative diseases
of the nervous system, in particular the cerebellum, and other systems that manifest with a …