Recent developments of gallic acid derivatives and their hybrids in medicinal chemistry: A review

NAAL Zahrani, RM El-Shishtawy, AM Asiri - European journal of medicinal …, 2020 - Elsevier
The leading cause of several degenerative diseases such as atherosclerosis, cancer, aging,
cardiovascular, and inflammatory diseases is oxidative stress, a consequence of …

Gallic acid for cancer therapy: Molecular mechanisms and boosting efficacy by nanoscopical delivery

M Ashrafizadeh, A Zarrabi, S Mirzaei, F Hashemi… - Food and Chemical …, 2021 - Elsevier
Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site

L Li, S Jiang, X Li, Y Liu, J Su, J Chen - European journal of medicinal …, 2018 - Elsevier
Microtubules (composed of α-and β-tubulin heterodimers) play a pivotal role in mitosis and
cell division, and are regarded as an excellent target for chemotherapeutic agents to treat …

Bioactive aurones, indanones, and other hemiindigoid scaffolds: medicinal chemistry and photopharmacology perspectives

LM Lazinski, G Royal, M Robin… - Journal of Medicinal …, 2022 - ACS Publications
Hemiindigoids comprise a range of natural and synthetic scaffolds that share the same
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …

Antifungal Activity of Gallic Acid In Vitro and In Vivo

ZJ Li, M Liu, G Dawuti, Q Dou, Y Ma… - Phytotherapy …, 2017 - Wiley Online Library
Gallic acid (GA) is a polyphenol natural compound found in many medicinal plant species,
including pomegranate rind (Punica granatum L.), and has been shown to have …

Recent developments in biological activities of indanones

SA Patil, R Patil, SA Patil - European journal of medicinal chemistry, 2017 - Elsevier
Indanone is one of the privileged structures in medicinal chemistry and it's commonly
associated with various pharmacologically active compounds. The indanone moiety is found …

Medicinal chemistry of indane and its analogues: A mini review

P Prasher, M Sharma - ChemistrySelect, 2021 - Wiley Online Library
Abstract 'Indane′ and its analogues indene, 1‐indenone, and 1, 3‐indandione present an
attractive biological profile for the rational development of therapeutic molecules. The …

RNA m6A methylation regulators in ovarian cancer

J Guo, J Zheng, H Zhang, J Tong - Cancer cell international, 2021 - Springer
Abstract N6-methyladenosine (m6A) is the most abundant RNA modification of mammalian
mRNAs and plays a vital role in many diseases, especially tumours. In recent years, m6A …

Virtual screening, Docking, ADMET and System Pharmacology studies on Garcinia caged Xanthone derivatives for Anticancer activity

S Alam, F Khan - Scientific reports, 2018 - nature.com
Caged xanthones are bioactive compounds mainly derived from the Garcinia genus. In this
study, a structure-activity relationship (SAR) of caged xanthones and their derivatives for …

A Review of various aspects of the Ethnopharmacological, Phytochemical, Pharmacognostical, and Clinical significance of selected Medicinal plants

A Singh - Asian Journal of Pharmacy and Technology, 2022 - indianjournals.com
Traditional medicine is a body of knowledge, skills, and practices based on traditional
cultures' presumptions, beliefs, and experiences in order to maintain their health. Traditional …