Cerebral microvascular pathology in aging and Alzheimer's disease
E Farkas, PGM Luiten - Progress in neurobiology, 2001 - Elsevier
The aging of the central nervous system and the development of incapacitating neurological
diseases like Alzheimer's disease (AD) are generally associated with a wide range of …
diseases like Alzheimer's disease (AD) are generally associated with a wide range of …
Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications
J Wess - Annu. Rev. Pharmacol. Toxicol., 2004 - annualreviews.org
Muscarinic acetylcholine receptors (mAChRs; M1–M5) play key roles in regulating the
activity of many important functions of the central and peripheral nervous system. Because of …
activity of many important functions of the central and peripheral nervous system. Because of …
Distribution and function of the muscarinic receptor subtypes in the cardiovascular system
HC Saternos, DA Almarghalani… - Physiological …, 2018 - journals.physiology.org
Muscarinic acetylcholine receptors belong to the G protein-coupled receptor superfamily
and are widely known to mediate numerous functions within the central and peripheral …
and are widely known to mediate numerous functions within the central and peripheral …
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation
L Ma, MA Seager, M Wittmann… - Proceedings of the …, 2009 - National Acad Sciences
The forebrain cholinergic system promotes higher brain function in part by signaling through
the M1 muscarinic acetylcholine receptor (mAChR). During Alzheimer's disease (AD), these …
the M1 muscarinic acetylcholine receptor (mAChR). During Alzheimer's disease (AD), these …
[HTML][HTML] Theories of schizophrenia: a genetic-inflammatory-vascular synthesis
DR Hanson, II Gottesman - BMC medical genetics, 2005 - Springer
Background Schizophrenia, a relatively common psychiatric syndrome, affects virtually all
brain functions yet has eluded explanation for more than 100 years. Whether by …
brain functions yet has eluded explanation for more than 100 years. Whether by …
Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice
M Yamada, KG Lamping, A Duttaroy… - Proceedings of the …, 2001 - National Acad Sciences
The M5 muscarinic receptor is the most recent member of the muscarinic acetylcholine
receptor family (M1-M5) to be cloned. At present, the physiological relevance of this receptor …
receptor family (M1-M5) to be cloned. At present, the physiological relevance of this receptor …
[PDF][PDF] Expression of non-neuronal acetylcholine in lymphocytes and its contribution to the regulation of immune function
K Kawashima, T Fujii - Front Biosci, 2004 - researchgate.net
[Frontiers in Bioscience 9, 2063-2085, September 1, 2004] 2063 EXPRESSION OF NON-NEURONAL
ACETYLCHOLINE IN LYMPHOCYTES AND ITS C Page 1 [Frontiers in Bioscience 9, 2063-2085 …
ACETYLCHOLINE IN LYMPHOCYTES AND ITS C Page 1 [Frontiers in Bioscience 9, 2063-2085 …
Human development: Biological and genetic processes
II Gottesman, DR Hanson - Annu. Rev. Psychol., 2005 - annualreviews.org
Adaptation is a central organizing principle throughout biology, whether we are studying
species, populations, or individuals. Adaptation in biological systems occurs in response to …
species, populations, or individuals. Adaptation in biological systems occurs in response to …
Muscarinic receptor subtype pharmacology and physiology
RM Eglen - Progress in medicinal chemistry, 2005 - Elsevier
Publisher Summary The role of muscarinic receptors is highly complex. The recent
pharmacological evidence with novel compounds, together with data from transgenic mice …
pharmacological evidence with novel compounds, together with data from transgenic mice …
Relative contributions of sympathetic, cholinergic, and myogenic mechanisms to cerebral autoregulation
Background and Purpose—Prior work aimed at improving our understanding of human
cerebral autoregulation has explored individual physiological mechanisms of autoregulation …
cerebral autoregulation has explored individual physiological mechanisms of autoregulation …