Beyond plasticity: the dynamic impact of electrical synapses on neural circuits
P Alcamí, AE Pereda - Nature Reviews Neuroscience, 2019 - nature.com
Electrical synapses are found in vertebrate and invertebrate nervous systems. The cellular
basis of these synapses is the gap junction, a group of intercellular channels that mediate …
basis of these synapses is the gap junction, a group of intercellular channels that mediate …
[HTML][HTML] Electrical synapses in mammalian CNS: Past eras, present focus and future directions
JI Nagy, AE Pereda, JE Rash - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
Gap junctions provide the basis for electrical synapses between neurons. Early studies in
well-defined circuits in lower vertebrates laid the foundation for understanding various …
well-defined circuits in lower vertebrates laid the foundation for understanding various …
[HTML][HTML] Role of olivary electrical coupling in cerebellar motor learning
RS Van Der Giessen, SK Koekkoek, S van Dorp… - Neuron, 2008 - cell.com
The level of electrotonic coupling in the inferior olive is extremely high, but its functional role
in cerebellar motor control remains elusive. Here, we subjected mice that lack olivary …
in cerebellar motor control remains elusive. Here, we subjected mice that lack olivary …
[HTML][HTML] Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network
Tonic motor control involves oscillatory synchronization of activity at low frequency (5–30
Hz) throughout the sensorimotor system, including cerebellar areas. We investigated the …
Hz) throughout the sensorimotor system, including cerebellar areas. We investigated the …
Neuronal gap junctions: making and breaking connections during development and injury
AB Belousov, JD Fontes - Trends in neurosciences, 2013 - cell.com
In the mammalian central nervous system (CNS), coupling of neurons by gap junctions (ie,
electrical synapses) and the expression of the neuronal gap junction protein, connexin 36 …
electrical synapses) and the expression of the neuronal gap junction protein, connexin 36 …
Electrical synapses control hippocampal contributions to fear learning and memory
The role of electrical synapses in synchronizing neuronal assemblies in the adult
mammalian brain is well documented. However, their role in learning and memory …
mammalian brain is well documented. However, their role in learning and memory …
Oculopalatal tremor explained by a model of inferior olivary hypertrophy and cerebellar plasticity
The inferior olivary nuclei clearly play a role in creating oculopalatal tremor, but the exact
mechanism is unknown. Oculopalatal tremor develops some time after a lesion in the brain …
mechanism is unknown. Oculopalatal tremor develops some time after a lesion in the brain …
Cerebellar inhibitory input to the inferior olive decreases electrical coupling and blocks subthreshold oscillations
GABAergic projection neurons in the cerebellar nuclei (CN) innervate the inferior olive (IO)
that in turn is the source of climbing fibers targeting Purkinje neurons in the cerebellar …
that in turn is the source of climbing fibers targeting Purkinje neurons in the cerebellar …
The computational power of the human brain
PJ Gebicke-Haerter - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
At the end of the 20th century, analog systems in computer science have been widely
replaced by digital systems due to their higher computing power. Nevertheless, the question …
replaced by digital systems due to their higher computing power. Nevertheless, the question …
[HTML][HTML] Harmaline tremor: underlying mechanisms in a potential animal model of essential tremor
A Handforth - Tremor and other hyperkinetic movements, 2012 - ncbi.nlm.nih.gov
Background Harmaline and harmine are tremorigenic β-carbolines that, on administration to
experimental animals, induce an acute postural and kinetic tremor of axial and truncal …
experimental animals, induce an acute postural and kinetic tremor of axial and truncal …