The SH-SY5Y cell line: a valuable tool for Parkinson's disease drug discovery

M Pandey, V Karmakar, A Majie… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Owing to limited efficient treatment strategies for highly prevalent and
distressing Parkinson's disease (PD), an impending need emerged for deciphering new …

Nanotechnology in the diagnostic and therapy for Alzheimer's disease

A Panghal, SJS Flora - Biochimica et Biophysica Acta (BBA)-General …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by β-
amyloid plaque, intraneuronal tangles, significant neuronal loss and cognitive deficit …

An update on pathogenesis and clinical scenario for Parkinson's disease: diagnosis and treatment

H Adam, SCB Gopinath, MK Md Arshad, T Adam… - 3 Biotech, 2023 - Springer
In severe cases, Parkinson's disease causes uncontrolled movements known as motor
symptoms such as dystonia, rigidity, bradykinesia, and tremors. Parkinson's disease also …

Nanozymes: Potential Therapies for Reactive Oxygen Species Overproduction and Inflammation in Ischemic Stroke and Traumatic Brain Injury

Y Yang, Z Li, X Fan, C Jiang, J Wang… - ACS …, 2024 - ACS Publications
Nanozymes, which can selectively scavenge reactive oxygen species (ROS), have recently
emerged as promising candidates for treating ischemic stroke and traumatic brain injury …

[HTML][HTML] Dopamine and Citicoline-Co-Loaded Solid Lipid Nanoparticles as Multifunctional Nanomedicines for Parkinson's Disease Treatment by Intranasal …

S Castellani, GN Iaconisi, F Tripaldi, V Porcelli… - Pharmaceutics, 2024 - mdpi.com
This work aimed to evaluate the potential of the nanosystems constituted by dopamine (DA)
and the antioxidant Citicoline (CIT) co-loaded in solid lipid nanoparticles (SLNs) for …

Vanadium‐Incorporated Mesoporous Silica as Oxidase Mimic for Colorimetric Dopamine Detection and Anticancer Activity

R Biswas, D Ghosh, S Dasgupta, SN Bhaduri… - …, 2023 - Wiley Online Library
The intriguing features of artificial enzymes made nanozymes attractive in the field of
biosensing and biomedical. Here, vanadium‐incorporated dendritic mesoporous silica …

Nanomedicine and drug delivery: A comprehensive review of applications and challenges

K Singh, S Singhal, S Pahwa, VA Sethi… - Nano-Structures & Nano …, 2024 - Elsevier
Nanotechnology is instrumental across various fields of life, offering transformative
approaches to solving complex problems. At the core of this innovation is nanomedicine, a …

[HTML][HTML] Nanogap nanowires and its applications in biosensing

AKY Dafhalla, TS Dhahi, AW Al-Mufti, SA Saad… - Sensing and Bio …, 2024 - Elsevier
Nanogap nanowires have gained attention for their potential applications in biosensing due
to their unique physical properties, such as high surface-to-volume ratios and enhanced …

Some Novel Therapies in Parkinson's Disease: A Promising Path Forward or Not Yet? A Systematic Review of the Literature

A Bougea - Biomedicines, 2024 - mdpi.com
In light of the unsuccessful traditional therapies for Parkinson's disease (PD) overmany
years, there is an unmet need for the development of novel therapies to alleviate the …

纳米酶在脑疾病治疗中的应用

孟子楹, 王杰, 王嘉璞, 魏延, 黄棣, 梁紫微 - 化学进展, 2024 - manu56.magtech.com.cn
摘要近年来, 作为新一代人工酶的纳米酶, 凭借着优于天然酶的多酶活性, 高稳定性和靶向性等
特点逐步进入医学领域, 又因对活性氧的调控作用而被应用于多种疾病及癌症的治疗 …