Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Gallium-68 (68Ga) is a positron-emitting isotope used for clinical PET imaging of peptide
receptor expression. 68Ga radiopharmaceuticals used in molecular PET imaging consist of …

Receptor-based radiopharmaceuticals are of great current interest in molecular imaging and
radiotherapy of cancers, and provide a unique tool for target-specific delivery of …

Integrin αvβ3 plays a significant role in tumor angiogenesis and is a receptor for the
extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide …

The objective of medical imaging using molecular probes and perfusion radiotracers is to
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …

Purpose Gallium-68 is a metallic positron emitter with a half-life of 68 min that is ideal for the
in vivo use of small molecules, such as [68 Ga-DOTA, Tyr 3] octreotide, in the diagnostic …

Somatostatin-based radiolabeled peptides have been successfully introduced into the clinic
for targeted imaging and radionuclide therapy of somatostatin receptor (sst)–positive tumors …

Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-
life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five …