MOF as nanoscale drug delivery devices: Synthesis and recent progress in biomedical applications

M Moharramnejad, A Ehsani, M Shahi… - Journal of Drug Delivery …, 2023 - Elsevier
Metal-organic frameworks (MOFs) have received a lot of attention for application as
nanoscale drug delivery devices due to their unique properties in high storage capacities …

Nanomedicine applications of hybrid nanomaterials built from metal–ligand coordination bonds: nanoscale metal–organic frameworks and nanoscale coordination …

C He, D Liu, W Lin - Chemical reviews, 2015 - ACS Publications
The past two decades have witnessed rapid developments and innovations in
nanotechnology. 1− 10 Significant efforts have also been devoted to exploring clinical …

MIL-100 (Fe) a potent adsorbent of Dacarbazine: Experimental and molecular docking simulation

M Barjasteh, M Vossoughi, M Bagherzadeh… - Chemical Engineering …, 2023 - Elsevier
Dacarbazine (DTIC) is a commonly used anticancer drug that has been found in
pharmaceutical and hospital wastewater, posing a risk to human health and aquatic …

Nanoporous metal organic frameworks as hybrid polymer–metal composites for drug delivery and biomedical applications

S Beg, M Rahman, A Jain, S Saini, P Midoux… - Drug Discovery …, 2017 - Elsevier
Highlights•Metal organic frameworks (MOFs) are nanoporous hybrid polymer–metal
composites of unique structures, tunable pore size and volume.•MOFs possess excellent …

Composite CD-MOF nanocrystals-containing microspheres for sustained drug delivery

H Li, N Lv, X Li, B Liu, J Feng, X Ren, T Guo, D Chen… - Nanoscale, 2017 - pubs.rsc.org
Metal–organic frameworks (MOFs), which are typically embedded in polymer matrices as
composites, are emerging as a new class of carriers for sustained drug delivery. Most of the …

A designable magnetic MOF composite and facile coordination-based post-synthetic strategy for the enhanced removal of Hg 2+ from water

L Huang, M He, B Chen, B Hu - Journal of Materials Chemistry A, 2015 - pubs.rsc.org
A magnetic MOF composite was successfully prepared by a novel and green strategy
through reasonable design. The nano Fe3O4@ SiO2 core was first coated by a shell of Cu …

Construction of well interconnected metal-organic framework structure for effectively promoting proton conductivity of proton exchange membrane

Z Rao, K Feng, B Tang, P Wu - Journal of Membrane Science, 2017 - Elsevier
To obtain proton exchange membrane (PEM) with high proton conductivities under both
high humidity and anhydrous condition, interconnected UiO-66-NH 2 was tethered onto …

ZIF-8 as a promising drug delivery system for benznidazole: development, characterization, in vitro dialysis release and cytotoxicity

LR de Moura Ferraz, AÉGA Tabosa… - Scientific reports, 2020 - nature.com
Chagas disease (CD), caused by the flagellate protozoan Trypanosoma cruzi, is one of the
major public health problems in developing countries. Benznidazole (BNZ) is the only drug …

Exploring a thiol-functionalized MOF for elimination of lead and cadmium from aqueous solution

J Zhang, Z Xiong, C Li, C Wu - Journal of Molecular Liquids, 2016 - Elsevier
A thiol-functionalized metal organic framework material (called HS-mSi@ MOF-5) was
successfully prepared by the thiol modification which taking the silica gel layer as a medium …

Review of computer simulations on anti-cancer drug delivery in MOFs

M Kotzabasaki, GE Froudakis - Inorganic Chemistry Frontiers, 2018 - pubs.rsc.org
Metal–organic frameworks (MOFs) have been recently used as potential nanocarrier
platforms in biomedical applications such as drug storage and delivery, due to their low …