The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …

Following their exit from the thymus, T cells are endowed with potent effector functions but
must spare host tissue from harm. The fate of these cells is dictated by a series of …

Follicular helper T (TFH) cells are a specialized subset of CD4+ T cells that essentially
support germinal center responses where high-affinity and long-lived humoral immunity is …

A growing body of evidence indicates that, over the course of evolution of the immune
system, arginine has been selected as a node for the regulation of immune responses. An …

Simple Summary Cancer cells are consistently under oxidative stress, as reflected by
elevated basal level of reactive oxygen species (ROS), due to increased metabolism driven …

Accumulating evidence suggests that oxidative stress plays a major role in the pathogenesis
of multiple sclerosis (MS). Reactive oxygen species (ROS), which if produced in excess lead …

Reactive oxygen species (ROS) are derivatives of molecular oxygen (O 2) involved in
various physiological and pathological processes. In immune cells, ROS are mediators of …

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with limited response to
cytotoxic chemoradiotherapy, as well as newer immunotherapies. The PDA tumor …

Abstract l-Arginine is an essential amino acid for birds and young mammals, and it is a
conditionally essential amino acid for adult mammals, as it is important in situations in which …

During normal cellular activities, various processes inside of cells produce reactive oxygen
species (ROS). Some of the most common ROS are hydrogen peroxide (H2O2), superoxide …