L-Glutaminase Synthesis by Marine Halomonas meridiana Isolated from the Red Sea and Its Efficiency against Colorectal Cancer Cell Lines

YS Mostafa, SA Alamri, MY Alfaifi, SA Alrumman… - Molecules, 2021 - mdpi.com
L-glutaminase is an important anticancer agent that is used extensively worldwide by
depriving cancer cells of L-glutamine. The marine bacterium, Halomonas meridian was …

Molecular characterization and computational analysis of a highly specific L-glutaminase from a marine bacterium Bacillus australimaris NIOT30

N Thenmozhi Kulasekaran, Vanlalrovi… - Scientific Reports, 2024 - nature.com
An alkaline active L-glutaminase (BALG) producing bacterium was screened and identified
from seamount sediment samples of the Arabian Sea. The isolate was confirmed to be …

Antarctic marine sediment as a source of filamentous fungi-derived antimicrobial and antitumor compounds of pharmaceutical interest

KF Camacho, L de Melo Carlos, SPF Bernal… - Extremophiles, 2024 - Springer
Antarctica harbors a microbial diversity still poorly explored and of inestimable
biotechnological value. Cold-adapted microorganisms can produce a diverse range of …

Screening and optimization of a nitrate reductase-producing Staphylococcus simulans UV-11 and its application

M Sun, X Ning - Journal of Food Measurement and Characterization, 2021 - Springer
A strain of Staphylococcus simulans D14 (S. simulans D14) showed the highest nitrate
reductase activity (NRA) of 4.52 mM NO 2−/mg dry weight by the spectrophotometric …

Statistical optimization of the bioconversion of agricultural residue into L-glutaminase enzyme by Aspergillus terreus ZHG2 under solid-state fermentation

ZH Wardah, HG Chaudhari, A Das, VS Prajapati… - Biologia, 2024 - Springer
L-glutaminase is an amidohydrolase that can be an effective chemotherapeutic tool for
treating a variety of cancers in addition to its use in the food sector to break down acrylamide …

Multi Gene Genetic Program Modelling on L-Asparaginase Activity of Bacillus Stratosphericus

M Pola, C Potla Durthi, RR Erva… - Chemical Product and …, 2020 - degruyter.com
The current study focuses on maximization of L-Asparaginase production from Bacillus
stratosphericus isolated from Ocimum tenuiflorum. Optimization study followed by modelling …

Effective use of screening experiments: Some practical experiences

RD Snee, SP Bailey - Applied Stochastic Models in Business …, 2023 - Wiley Online Library
When faced with a problem to be solved by running designed experiments we should first
think of what strategy should be used for the experimentation. One aspect of successful …